A0A6C0WW93 · A0A6C0WW93_ACISI
- ProteinMitochondrial uncoupling protein 2
- GeneUCP2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids310 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- (S)-malate(out) + phosphate(in) + H+(in) = (S)-malate(in) + phosphate(out) + H+(out)(S)-malate (out)CHEBI:15589
+ phosphate (in)CHEBI:43474+ H+ (in)CHEBI:15378= (S)-malate (in)CHEBI:15589+ phosphate (out)CHEBI:43474+ H+ (out)CHEBI:15378 - (S)-malate(out) = (S)-malate(in)
- L-aspartate(out) + phosphate(in) + H+(in) = L-aspartate(in) + phosphate(out) + H+(out)
- malonate(out) + phosphate(in) + H+(in) = malonate(in) + phosphate(out) + H+(out)
- oxaloacetate(out) + phosphate(in) + H+(in) = oxaloacetate(in) + phosphate(out) + H+(out)
- sulfate(out) + phosphate(in) + H+(in) = sulfate(in) + phosphate(out) + H+(out)
- H+(in) = H+(out)
- L-aspartate(out) = L-aspartate(in)
- a long-chain fatty acid(out) = a long-chain fatty acid(in)
- chloride(in) = chloride(out)
- phosphate(in) = phosphate(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | oxidative phosphorylation uncoupler activity | |
Biological Process | adaptive thermogenesis | |
Biological Process | mitochondrial transmembrane transport | |
Biological Process | response to cold |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMitochondrial uncoupling protein 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Chondrostei > Acipenseriformes > Acipenseridae > Acipenser
Accessions
- Primary accessionA0A6C0WW93
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 11-106 | Solcar | ||||
Sequence: PTAAVKFIGAGTAACIADLVTFPLDTAKVRLQLQGECKSAGASVTSVRYSGVFGTITTMVRTEGARSLYNGLVAGLQRQMSFASVRIGLYDSVKQF | ||||||
Repeat | 114-204 | Solcar | ||||
Sequence: AGIGSRLLAGCTTGAMAVALAQPTDVVKVRFQAQANGSSGNRRYQGTMQAYKTIAKEEGVKGLWKGTSPNIARNAIVNCTELVTYDLIKDA | ||||||
Repeat | 213-298 | Solcar | ||||
Sequence: DTLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSAQGQYCSALNCAFTMMKKEGPTAFYKGFMPSFLRLGSWNVVMFVTYEQLKRG |
Sequence similarities
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length310
- Mass (Da)33,322
- Last updated2020-06-17 v1
- ChecksumF27A7D8239A9DCFA