A0A6B9KZE1 · A0A6B9KZE1_9GEMI

Function

function

Binds to the genomic viral ssDNA, shuttles it into and out of the cell nucleus. Begomoviruses use 2 proteins to transport their DNA from cell to cell. The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates movement across the cell wall.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell
Cellular Componenthost cell cytoplasm
Cellular Componenthost cell nucleus
Cellular Componenthost cell plasma membrane
Cellular Componentmembrane
Cellular Componentviral capsid
Molecular Functionsingle-stranded DNA binding
Molecular Functionstructural molecule activity
Biological ProcessDNA transport
Biological Processtransport of virus in host, cell to cell

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Nuclear shuttle protein
  • Short names
    NSP

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • EuMV-B.CD-W
  • Taxonomic lineage
    Viruses > Monodnaviria > Shotokuvirae > Cressdnaviricota > Repensiviricetes > Geplafuvirales > Geminiviridae > Begomovirus

Accessions

  • Primary accession
    A0A6B9KZE1

Subcellular Location

Cytoplasm
Host cell membrane
; Peripheral membrane protein
Host cytoplasm
Host nucleus

Keywords

Interaction

Subunit

Binds to single-stranded and double-stranded viral DNA. Interacts with the host nuclear shuttle interacting (NSI) protein. This interaction may allow NSP to recruit NSI monomers to the viral genome and thus regulate nuclear export of viral genome by NSP.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-52Disordered
Compositional bias9-33Basic residues
Compositional bias34-52Basic and acidic residues

Sequence similarities

Belongs to the begomovirus nuclear shuttle protein family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    256
  • Mass (Da)
    29,651
  • Last updated
    2020-06-17 v1
  • Checksum
    2764B54A01E8AB3B
MYSTKYRRGGSTSHRRFNSRNTLFKRQHPSRRVDYRRRPSSPNKANDDSKMVNQRIHEDQFGPEFVLAHNMALSSYISFPSLTRTEPNRSRSYIKLRRLRYKGTLKIERVQSDMNLDGSSPKIEGVFTMVVVVDRKPHLNPTGCLHTFDDLFGARIHSHGNLTITPSLKDRFYIRHVMKRVLSVEKDSLMVDLEGSTALSNRRVNCWAAFRDLDRDSCNGVYANISKNALLVYYCWMSDAMSKASTFVSFDLDYFG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias9-33Basic residues
Compositional bias34-52Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN203161
EMBL· GenBank· DDBJ
QHB15473.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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