A0A6B9FFJ0 · A0A6B9FFJ0_9HYPH

Function

function

Maintains high levels of reduced glutathione.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

146050100150200250300350400450
TypeIDPosition(s)Description
Binding site52FAD (UniProtKB | ChEBI)
Binding site177-184NAD+ (UniProtKB | ChEBI)
Binding site263NAD+ (UniProtKB | ChEBI)
Binding site304FAD (UniProtKB | ChEBI)
Active site437Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglutathione-disulfide reductase (NADPH) activity
Molecular FunctionNADP binding
Biological Processcell redox homeostasis
Biological Processglutathione metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione reductase
  • EC number
  • Short names
    GRase

Gene names

    • Name
      gor
    • ORF names
      MMSR116_06815

Organism names

Accessions

  • Primary accession
    A0A6B9FFJ0

Proteomes

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond43↔48Redox-active

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-319FAD/NAD(P)-binding
Domain339-447Pyridine nucleotide-disulphide oxidoreductase dimerisation

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    460
  • Mass (Da)
    49,453
  • Last updated
    2020-06-17 v1
  • Checksum
    1976020C4E271AF2
MSAFDVDLFVIGGGSGGVRAARIAAGYGARVMLAEEYRVGGTCVIRGCVPKKLMVYAGRFADEFEDAAGFGWTVEKPRFDWGILKRRRDAEVTRLEGIYDANLIRAGVEIVPERAVIEDPHTVRLVGSGRTVRTERILVAVGGHPVKEPAVPGIEHAITSNEVFELESLPERILVVGGGYIAVEFAGIFAALGSRTTLLHRGDRLLRGFDDEVRDALAEAYRQRMDLRLGRSLTRLERRDDGLVAQLDDGSAIEADQILVATGRRPNVAGLGLDRVGIETDAAGAIPVDAYSQTTVPSIYAVGDVTNRANLTPVAIREGHAFADTVFGGKPSCVDHRLIPTAVFSTPEIGVVGHTEAAAREVYGKIDVYKARFRPMKATLSGREERILMKVLVDCASDRVVGVHIFGHDAGEVIQAVGIAVTMGATKADFDRTVAVHPTAAEELVTMRVPEVTKHPVGVG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP043538
EMBL· GenBank· DDBJ
QGY01640.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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