A0A6B8JPX6 · A0A6B8JPX6_9GAMM
- ProteinCatalase-peroxidase
- GenekatG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids725 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Catalytic activity
- 2 H2O2 = O2 + 2 H2O
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
Features
Showing features for site, active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to hydrogen peroxide | |
Biological Process | hydrogen peroxide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCatalase-peroxidase
- EC number
- Short namesCP
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Ectothiorhodospiraceae > Spiribacter
Accessions
- Primary accessionA0A6B8JPX6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Cross-link | 226↔252 | Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98) | ||||
Sequence: YVNPEGVNGNPDPLKTAEQVRVTFARM |
Post-translational modification
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
Interaction
Subunit
Homodimer or homotetramer.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 106-125 | Disordered | ||||
Sequence: TSDGRGGGGTGNQRFAPLNS | ||||||
Compositional bias | 110-125 | Polar residues | ||||
Sequence: RGGGGTGNQRFAPLNS | ||||||
Domain | 132-426 | Plant heme peroxidase family profile | ||||
Sequence: LDKARRLLWPLKQKYGNQVSWADLIILAGTVSYESMGLKVFGFGYGREDIWHPEKDIYWGSEKEWLAPSEERYEDVEQPETMENPLAAVQMGLIYVNPEGVNGNPDPLKTAEQVRVTFARMAMNDEETVALTAGGHTVGKCHGNGDAELLGPDPEAADVEEQGLGWNNHSTRGVGRDTVTSGIEGAWTTHPTQWDNGYFDLLFNYDWELKKSPAGAWQWEPVDIKEEDKPVDVEDPSIRLNPIMTDADMAMIKDPAYRKISERFYNDPEYFSEVFARAWFKLTHRDMGPKARYIG |
Sequence similarities
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length725
- Mass (Da)80,821
- Last updated2020-06-17 v1
- ChecksumE8F64658D54FC450
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 110-125 | Polar residues | ||||
Sequence: RGGGGTGNQRFAPLNS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP046046 EMBL· GenBank· DDBJ | QGM21878.1 EMBL· GenBank· DDBJ | Genomic DNA |