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A0A6B3QEU5 · A0A6B3QEU5_ENTFC

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site9-16ATP (UniProtKB | ChEBI)
Binding site11-16substrate
Site100Interaction with substrate tRNA
Site124Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • ORF names
      G3385_09690

Organism names

Accessions

  • Primary accession
    A0A6B3QEU5

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region34-37Interaction with substrate tRNA

Sequence similarities

Belongs to the IPP transferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    305
  • Mass (Da)
    34,860
  • Last updated
    2020-06-17 v1
  • MD5 Checksum
    31859ED437330F6443B6127BD537ACE4
MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDIGTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANREHLPIIAGGTGLYIQSLLYDYQLGATEEANPEIRKKYETLAETTGSQALWNQLKEKDPAAAEKIHWNNQRKVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLVAEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNRLDAQWFDLISEPNQKSQIEQTIKKWLEAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAHCB010000103
EMBL· GenBank· DDBJ
NEU46075.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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