A0A6B0RDK0 · A0A6B0RDK0_9CETA

  • Protein
    Aldo-keto reductase family 1 member A1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site, site, binding site.

Type
IDPosition(s)Description
Active site81Proton donor
Site111Lowers pKa of active site Tyr
Binding site144substrate

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcytosol
Cellular Componentribosome
Molecular Functionaldose reductase (NADPH) activity
Molecular Functionallyl-alcohol dehydrogenase activity
Molecular Functionglucuronolactone reductase activity
Molecular FunctionL-glucuronate reductase activity
Molecular Functionstructural constituent of ribosome
Biological Processaldehyde catabolic process
Biological Processtranslation

Keywords

  • Ligand
    • #NADP

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aldo-keto reductase family 1 member A1
  • EC number
  • Alternative names
    • Alcohol dehydrogenase [NADP(+)]
    • Aldehyde reductase
    • Glucuronate reductase
    • Glucuronolactone reductase
    • S-nitroso-CoA reductase

Gene names

    • ORF names
      E5288_WYG016997

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • WY2019
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A6B0RDK0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-324NADP-dependent oxidoreductase

Sequence similarities

Belongs to the aldo/keto reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    356
  • Mass (Da)
    40,148
  • Last updated
    2020-06-17 v1
  • Checksum
    9446CDB30C316A74
MHIRKATKYLKDVTLKKQCVPFRRYNGGVGAMAASCILLHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGPGKLVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDSPFPKNADGTIRYDSTHYKETWRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAYSPLGSSDRAWRDPEEPVLLKEPVVLALAEKHGRSPAQILLRWQVQRKVSCIPKSVTPSRILENIQVFDFAFSPEEMKQLDALNKNLRFIVPMLTVDGKRVPRDAGHPLYPFNDPY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VBQZ03000044
EMBL· GenBank· DDBJ
MXQ88248.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help