A0A6B0RDK0 · A0A6B0RDK0_9CETA
- ProteinAldo-keto reductase family 1 member A1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids356 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 3-deoxyfructose + NADP+ = 3-deoxyglucosone + NADPH + H+
- S-nitroso-CoA + NADPH + H+ = sulfinamide-CoA + NADP+This reaction proceeds in the forward direction.
- S-nitrosoglutathione + NADPH + H+ = S-(hydroxysulfenamide)glutathione + NADP+
- hydroxyacetone + NADP+ = methylglyoxal + NADPH + H+
Features
Showing features for active site, site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 81 | Proton donor | |||
Site | 111 | Lowers pKa of active site Tyr | |||
Binding site | 144 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | cytosol | |
Cellular Component | ribosome | |
Molecular Function | aldose reductase (NADPH) activity | |
Molecular Function | allyl-alcohol dehydrogenase activity | |
Molecular Function | glucuronolactone reductase activity | |
Molecular Function | L-glucuronate reductase activity | |
Molecular Function | structural constituent of ribosome | |
Biological Process | aldehyde catabolic process | |
Biological Process | translation |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAldo-keto reductase family 1 member A1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0A6B0RDK0
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length356
- Mass (Da)40,148
- Last updated2020-06-17 v1
- Checksum9446CDB30C316A74
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VBQZ03000044 EMBL· GenBank· DDBJ | MXQ88248.1 EMBL· GenBank· DDBJ | Genomic DNA |