A0A6A7Y4P2 · A0A6A7Y4P2_9HYPH

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11ADP (UniProtKB | ChEBI)
Binding site11ATP (UniProtKB | ChEBI)
Binding site11sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site12ATP (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site15ADP (UniProtKB | ChEBI)
Binding site81glycerol (UniProtKB | ChEBI)
Binding site81sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site82glycerol (UniProtKB | ChEBI)
Binding site82sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site133glycerol (UniProtKB | ChEBI)
Binding site133sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site242glycerol (UniProtKB | ChEBI)
Binding site242sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site243glycerol (UniProtKB | ChEBI)
Binding site264ADP (UniProtKB | ChEBI)
Binding site264ATP (UniProtKB | ChEBI)
Binding site307ADP (UniProtKB | ChEBI)
Binding site307ATP (UniProtKB | ChEBI)
Binding site311ATP (UniProtKB | ChEBI)
Binding site410ADP (UniProtKB | ChEBI)
Binding site410ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      F0357_11100

Organism names

  • Taxonomic identifier
  • Strain
    • Sp-1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Segnochrobactraceae > Segnochrobactrum

Accessions

  • Primary accession
    A0A6A7Y4P2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-249Carbohydrate kinase FGGY N-terminal
Domain260-448Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    53,598
  • Last updated
    2020-06-17 v1
  • Checksum
    442EC35584C87030
MTHILAIDQGTTSSRAILFDAAMRLKAVAQQEFPQHFPASGWVEHDPADLWSSVAGTARAAIEQAGLTGADIAAIGITNQRETVVIWDRATGEPIHRAIVWQDRRTADLCARLKADGLEPEISAKTGLLIDPYFSATKIKWLLDHVEGARERARRGELAFGTVDCFLIWKLTDGAVHATDATNAARTMLYDIREGRWDEALCAAFGVPMAMLPEVRDCAAPYGTTRPDLFGRAIPILGVAGDQQAATVGQACFRPGMLKSTYGTGCFALLNTGDDLVASKNRLLGTIAYRLKGRTTYALEGSIFIAGAVVQWLRDGLKIIRHAAETHPLAEKADPAQDLVLVPAFTGLGAPYWRPDCRGAVFGLTRNSGPAEFARAALESVGYQTRDLLEAMHADWKDATAEGVLRVDGGMTASDWTMQFLADILGAPVDRPVVRETTALGAAYLAGLEAGLYPDPDAFAATWALERRFLPALDETTRTAKYARWRRAVEATMAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VWNA01000001
EMBL· GenBank· DDBJ
MQT13178.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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