A0A6A7SB73 · A0A6A7SB73_9ZZZZ
- Proteinaspartate-semialdehyde dehydrogenase
- Geneasd
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids371 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-aspartate 4-semialdehyde + NADP+ + phosphate = 4-phospho-L-aspartate + H+ + NADPH
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate-semialdehyde dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | protein dimerization activity | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | lysine biosynthetic process via diaminopimelate | |
Biological Process | methionine biosynthetic process | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameaspartate-semialdehyde dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageunclassified sequences > metagenomes > ecological metagenomes
Accessions
- Primary accessionA0A6A7SB73
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-123 | Semialdehyde dehydrogenase NAD-binding | ||||
Sequence: RIGFVGWRGMVGSVLMERMRAEGDFADIPEPVFFSTSQAGQPGPDVGKGSAPLGDARDIDALKAMDAIVTTQGGDYTGEVYEKLRNAGWQGYWIDAASTLRMADDSIIVLDPVNLDVIRKG |
Sequence similarities
Belongs to the aspartate-semialdehyde dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length371
- Mass (Da)39,832
- Last updated2020-06-17 v1
- ChecksumF54ED22042B2BC5E