A0A679HJ68 · A0A679HJ68_9BACT
- ProteinNAD kinase
- GeneppnK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids286 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- NAD+ + ATP = ADP + NADP+ + H+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 69 | Proton acceptor | |||
Binding site | 69-70 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 143-144 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 154 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 171 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 173 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 184-189 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 243 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Nitrospirota > Nitrospiria > Nitrospirales > Nitrospiraceae > Nitrospira
Accessions
- Primary accessionA0A679HJ68
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length286
- Mass (Da)30,951
- Last updated2020-06-17 v1
- Checksum525E3491BA0E51A8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP022671 EMBL· GenBank· DDBJ | BCA53530.1 EMBL· GenBank· DDBJ | Genomic DNA |