A0A679HJ68 · A0A679HJ68_9BACT

  • Protein
    NAD kinase
  • Gene
    ppnK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

128620406080100120140160180200220240260280
Type
IDPosition(s)Description
Active site69Proton acceptor
Binding site69-70NAD+ (UniProtKB | ChEBI)
Binding site143-144NAD+ (UniProtKB | ChEBI)
Binding site154NAD+ (UniProtKB | ChEBI)
Binding site171NAD+ (UniProtKB | ChEBI)
Binding site173NAD+ (UniProtKB | ChEBI)
Binding site184-189NAD+ (UniProtKB | ChEBI)
Binding site243NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      ppnK
    • Synonyms
      nadK
    • ORF names
      W02_06700

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KM1
  • Taxonomic lineage
    Bacteria > Nitrospirota > Nitrospiria > Nitrospirales > Nitrospiraceae > Nitrospira

Accessions

  • Primary accession
    A0A679HJ68

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    30,951
  • Last updated
    2020-06-17 v1
  • Checksum
    525E3491BA0E51A8
MKSKSIGILTKPKFPEVKSTLQAVLSWLRERNIEVLLDTTSATLLGETGGIQKTQLAGKADVLLVMGGDGTMLSAARLAGERGIPILGVNMGGLGFLTEVRLEHFYPSLERVFTNDYVLDERLMLGTHVHRHGETVAQGVVLNDVVVSKGTLARMIELRISIQGRFVTNLRGDGLIVSTPTGSTAYSLSAGGPIIHPTVQSLMLTPVCPHTLTHRPLIVEGSAEIEVTLTSKDEGAMATLDGQVGVALTQGDTVELKVSEHRTRLIRFPESNYYDVLREKLKWGDG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP022671
EMBL· GenBank· DDBJ
BCA53530.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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