A0A678XDL2 · A0A678XDL2_SPOEX

Function

function

Rapidly hydrolyzes choline released into the synapse.

Catalytic activity

Features

Showing features for active site.

169450100150200250300350400450500550600650
TypeIDPosition(s)Description
Active site313Acyl-ester intermediate
Active site439Charge relay system
Active site553Charge relay system

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Cellular Componentplasma membrane
Cellular Componentsynapse
Molecular Functionacetylcholinesterase activity
Biological Processacetylcholine catabolic process
Biological Processcholine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Carboxylic ester hydrolase
  • EC number

Gene names

    • ORF names
      HF086_008295

Organism names

  • Taxonomic identifier
  • Strain
    • TB_SE_WUR_2020
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Noctuoidea > Noctuidae > Amphipyrinae > Spodoptera

Accessions

  • Primary accession
    A0A678XDL2

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_502571196718-694Carboxylic ester hydrolase

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region17-49Disordered
Compositional bias18-32Basic and acidic residues
Compositional bias64-105Basic and acidic residues
Region64-118Disordered
Domain118-640Carboxylesterase type B

Sequence similarities

Belongs to the type-B carboxylesterase/lipase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    694
  • Mass (Da)
    78,047
  • Last updated
    2020-06-17 v1
  • Checksum
    EC836E3A010AAFFD
MRVVLAALTALAARALAGPHEHRARHHAPEHPPHFPAPAPPQPYRGHGEAVRYNPELDTILPRLEDHETSSKRAKFEDAETSSKRAKYDERFYSNHERADEEPMADEPQLGPDDDDPLVVRTRKGRVRGITLTAATGKKVDAWFGIPYAQKPVGDLRFRHPRPAESWGDEILNTTTLPHSCVQIIDTVFGDFPGAMMWNPNTDMQEDCLFINIVTPRPRPKNAAVMLWVFGGGFYSGTATLDVYDAKILVSEEKVVYVSMQYRVASLGFLFFDTPDVPGNAGLFDQLMALQWVKDNIAYFGGNPHNITLFGESAGAVSVSLHLLSPLSRNLFSQAIMQSGAATAPWAIISREESILRGIRLAEAVHCPHSRTDMGPMIECLRKKSPDELVNNEWGTLGICEFPFVPIIDGSFLDELPARSLAHQNFKKTNLLMGSNTEEGYYYILYYLTELFPKEENVGISREQYLQAVRELNPYVNDVGKQAIVFEYTDWLNPDDPIRNRNALDKMVGDYHFTCGVNEMAHRYAETGNNVFTYYYKHRSKNNPWPSWTGVMHGDEINYVFGEPLNPGKNYSPEEVEFSKRLMRYWANFARTGNPSINPSGESTKIYWPVHTATGREYLSLAVNSSTIGHGLRVKECAFWQKYLPQLMAATNKPEPPKNCTNSASPVKVPYEIFGVGVVIATGLAKTTMFKYIV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias18-32Basic and acidic residues
Compositional bias64-105Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK138518
EMBL· GenBank· DDBJ
AZB49078.1
EMBL· GenBank· DDBJ
mRNA
JACEFF010000610
EMBL· GenBank· DDBJ
KAH9634461.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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