A0A678X9S1 · A0A678X9S1_9SAUR

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    ND4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Scinciformata > Scincidae > Egerniinae > Liopholis

Accessions

  • Primary accession
    A0A678X9S1

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane31-49Helical
Transmembrane55-76Helical
Transmembrane88-107Helical
Transmembrane134-159Helical
Transmembrane180-199Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-148NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    205
  • Mass (Da)
    22,782
  • Last updated
    2020-06-17 v1
  • MD5 Checksum
    9FA1BB73A305B2EF809EC710A4D417C7
TKLYYPFIILAMWGIVMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAILLMIAHGLTSSMLFCLANTNYERTHSRTLILARGLQLILPLMVSWWLLANLMNMALPPTINFTGELLILTSTFNWSPVTIIMTGAGTLLTAIYSLHMFLMSQRGKLPPHTTQMNPTYTREHLPMVLHILPMLILLTKPALAMGPLS

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MF987670
EMBL· GenBank· DDBJ
AYP71003.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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