A0A674H6Z3 · A0A674H6Z3_TAEGU

Function

Catalytic activity

Features

Showing features for binding site, active site.

1758100200300400500600700
Type
IDPosition(s)Description
Binding site540-548ATP (UniProtKB | ChEBI)
Binding site568ATP (UniProtKB | ChEBI)
Active site672Proton acceptor

GO annotations

AspectTerm
Cellular Componentaxon terminus
Cellular Componentdendritic spine
Cellular Componentplasma membrane
Cellular Componentpostsynaptic density
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionbrain-derived neurotrophic factor binding
Molecular Functionbrain-derived neurotrophic factor receptor activity
Biological Processcell differentiation
Biological Processcellular response to brain-derived neurotrophic factor stimulus
Biological Processnervous system development
Biological Processpositive regulation of kinase activity
Biological Processpositive regulation of neuron projection development
Biological Processprotein phosphorylation
Biological Processregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processtrans-synaptic signaling by neuropeptide, modulating synaptic transmission

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase receptor
  • EC number

Gene names

    • Name
      NTRK2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    A0A674H6Z3

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane427-450Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-31
ChainPRO_502546669732-758Tyrosine-protein kinase receptor

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain196-281Ig-like
Region400-420Disordered
Compositional bias401-420Polar residues
Compositional bias469-492Polar residues
Region469-494Disordered
Domain534-758Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    758
  • Mass (Da)
    84,126
  • Last updated
    2020-06-17 v1
  • Checksum
    B5412B5554EA7668
MVSWRRRPGPGLAQLWGLCCLVLGCWPAALGCPASCGCSSWRIWCTGSSPGIASFPVPQRSAEGDNVTEIYIANQPNLESINDNEVGFYVGLKNLTVVDSGLRFVSRHAFVKNVNLQYINLSRNKLSSLSKKPFRHLGLSDLILVDNPFKCSCEIMWIKKFQETKFYTETQDLYCIDDNNKKTALLDMKVPNCDLPSANLSNYNITVVEGKSITLYCDTTGGPPPNVSWVVTNLVSNHESDTNKNPASLTIKNVSSMDSGLEISCVAENIVGEDQASAELTVFFAPNITFIESPTPDHHWCIPFTVKGNPKPTLQWFYEGAVLNESEYICTKIHVINQSEYHGCLQLDNPTHLNNGAYTLLAKNDYGEDEKRVDAHFMSVPGDGNGPILDPDVYEYETTPNDLGDATNNSNQITSTDVSNKENEDSITVYVVVGIAALVCTGLVITLIILKFGRHSKFGMKGPSSVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVHHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQGKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAGLMAEGNRPAELTQSQMLHIAQQIASGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEV

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A674GFH4A0A674GFH4_TAEGUNTRK2842
H0YY17H0YY17_TAEGUNTRK2808

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias401-420Polar residues
Compositional bias469-492Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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