A0A674GMP6 · A0A674GMP6_TAEGU

Function

Catalytic activity

  • H2O + N2-(1-hydroxy-2-oxoethyl)-GDP = GDP + glycolate + H+
  • H2O + N2-(1-hydroxy-2-oxoethyl)-GMP = glycolate + GMP + H+
  • H2O + N2-(1-hydroxy-2-oxoethyl)-GTP = glycolate + GTP + H+
  • H2O + N2-(1-hydroxy-2-oxoethyl)-dGTP = dGTP + glycolate + H+
  • H2O + N2-(1-hydroxy-2-oxopropyl)-GDP = GDP + H+ + lactate
  • H2O + N2-(1-hydroxy-2-oxopropyl)-GMP = GMP + H+ + lactate
  • H2O + N2-(1-hydroxy-2-oxopropyl)-GTP = GTP + H+ + lactate
  • H2O + N2-(1-hydroxy-2-oxopropyl)-dGTP = dGTP + H+ + lactate
  • H2O + N6-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] = glycolate + H+ + L-lysyl-[protein]
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • H2O + N6-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] = H+ + L-lysyl-[protein] + lactate
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • H2O + N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] = glycolate + H+ + L-arginyl-[protein]
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] = H+ + L-arginyl-[protein] + lactate
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • H2O + S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] = glycolate + H+ + L-cysteinyl-[protein]
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • H2O + S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] = H+ + L-cysteinyl-[protein] + lactate
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • an N2-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O = a guanosine in RNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + H+ + lactate
  • an N2-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + H+ + lactate

GO annotations

AspectTerm
Cellular Componentmembrane raft
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Functionoxidoreductase activity, acting on peroxide as acceptor
Molecular Functionprotein deglycase activity
Biological Processautophagy
Biological Processglycolate biosynthetic process
Biological Processglyoxal metabolic process
Biological Processinflammatory response
Biological Processresponse to oxidative stress
Biological Processsingle fertilization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    protein deglycase
  • EC number
  • Alternative names
    • Maillard deglycase
    • Parkinsonism-associated deglycase

Gene names

    • Name
      PARK7

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    A0A674GMP6

Proteomes

Subcellular Location

Membrane raft
Membrane
; Lipid-anchor

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-170DJ-1/PfpI

Sequence similarities

Belongs to the peptidase C56 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    191
  • Mass (Da)
    20,197
  • Last updated
    2020-06-17 v1
  • Checksum
    BB2FF3769B45A9C7
MASKRALVILAKGAEEMETVIPTDVMRRAGIKVTVAGLTGKEPVQCSRDVFICPDASLEDARKEGPYDVVVLPGGNLGAQNLSESAAVKDILKDQESRKGLIAAICAGPTALLAHGIGYGSKVTTHPLAKDKMMNGAHYSYSESRVEKDGNILTSRGPGTSFEFGLAIVETLLGKEVAEQSHETFLPPCTV

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
H0YWD3H0YWD3_TAEGUPARK7233
B5G3Z6B5G3Z6_TAEGUPARK7189
H1A2L3H1A2L3_TAEGUPARK7215

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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