A0A674GM26 · A0A674GM26_TAEGU

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Homodimerization via the leucine zipper domains is required for autophosphorylation.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site115-123ATP (UniProtKB | ChEBI)
Binding site136ATP (UniProtKB | ChEBI)
Active site243Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitogen-activated protein kinase kinase kinase
  • EC number

Gene names

    • Name
      MAP3K21

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    A0A674GM26

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, coiled coil, region, compositional bias.

Type
IDPosition(s)Description
Domain20-84SH3
Domain109-381Protein kinase
Coiled coil405-432
Region498-530Disordered
Compositional bias499-530Polar residues
Region707-739Disordered
Compositional bias712-738Polar residues
Region797-821Disordered
Region854-873Disordered
Region949-981Disordered
Compositional bias950-981Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,070
  • Mass (Da)
    118,903
  • Last updated
    2020-06-17 v1
  • Checksum
    477CAD91CE04C972
MALPDAGAAAAAAAAGGSGGPCPLWTALYDYEASGEDELSLRRGDVVEVLSQDAAVSGDDGWWAGKIRHRLGIFPANYVTRQPRGGAAAGGSGRGDPAGTLTEIDFQHLELQEIIGVGGFGKVYRATWRGREVAVKAARQDPDEDITATAESVRQEAKLFSMLRHPNIIALHGVCLREPNLCLVMEFARGGSLNRALAAAPGAAAARGGRRIPPHILVNWAVQIARGMLYLHDEAIVPILHRDLKSSNILLLEKMEHDDICNKTLKITDFGLAREWHRTTKMSAAGTYAWMAPEVIKSSMFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWEQDPHIRPSFALILEQLTAIEGAVMTEMPQESFHSMQDDWKLEIQQIFNELRTKEKELRSREEELTRAALQQKSQEELLKRREQQLAEREIDVLERELNIMIFQLNQEKPNVKKRKGKFKRSRLKLKDGHRISLPSDFQHKITVQASPNLDKRRSLNSNNSSPSSSPTIIPRLRAIQLIPKTDTHTANGRRNSVYVYQQDVDITSEYELPCGVMKKGKISLCFQVTSDESNRTWGRSTTYHQEEFEDVKRNFKKKGCTWGPSSVQTKDRADCKDKVRPLSDGSNPWSTVLMKNQKGVPLASLFVDQGACTDKKLIPEGLDSKRPKPIKLPNQAYINLPLWKDDQGENTVENESFEEGTSASSTNSTPQMTPTNSLSRTLHKKKTDSVLYGCAVLLASVALGLDIRELNKSQGPDELLPKDERKKRDGIFQRASKFRRSASPTRLQYKKEETSIPSLDPASDTVNLLSMPSISTKCLLQPDSEDAFLSTVLGDSGQCSSTDNFSSQTSESKREQRIHLAPNTVLTQLKSQPFSLGLKQESQNVPKDSSTKLCMLGHRRTLSDGSHFQTTANGVASTNDVSRLPVLSVPGTLPSPSFQQRSNHSGVSNEKQSAVNTISRPRPSSLRSKIDAWQIIPRIIKPNSKDSECSEDNVDPDVNFLPDTEQRTNCHMPSLLDIDVEGQNRDCTVPLCRMKSKTCRPSIYELEREFLS

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
H0ZIV1H0ZIV1_TAEGUMAP3K211023

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias499-530Polar residues
Compositional bias712-738Polar residues
Compositional bias950-981Polar residues

Keywords

Genome annotation databases

Similar Proteins

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