A0A674GEU4 · A0A674GEU4_TAEGU
- ProteinCalcium-transporting ATPase
- GeneATP2C1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids921 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Catalytic activity
- Ca2+(in) + ATP + H2O = Ca2+(out) + ADP + phosphate + H+Ca2+ (in)CHEBI:29108
+ CHEBI:30616 + CHEBI:15377 = Ca2+ (out)CHEBI:29108+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378 - Mn2+(in) + ATP + H2O = Mn2+(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | Golgi cisterna membrane | |
Cellular Component | Golgi membrane | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | P-type calcium transporter activity | |
Biological Process | intracellular calcium ion homeostasis | |
Biological Process | manganese ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCalcium-transporting ATPase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia
Accessions
- Primary accessionA0A674GEU4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus, Golgi stack membrane ; Multi-pass membrane protein
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 79-97 | Helical | |||
Transmembrane | 103-119 | Helical | |||
Transmembrane | 269-288 | Helical | |||
Transmembrane | 294-323 | Helical | |||
Transmembrane | 775-795 | Helical | |||
Transmembrane | 844-861 | Helical | |||
Transmembrane | 873-895 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Monomer. Homodimer.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 25-99 | Cation-transporting P-type ATPase N-terminal | |||
Region | 187-208 | Disordered | |||
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length921
- Mass (Da)100,663
- Last updated2020-06-17 v1
- Checksum025D6949E045F37E
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A674H7C4 | A0A674H7C4_TAEGU | ATP2C1 | 956 | ||
H0Z163 | H0Z163_TAEGU | ATP2C1 | 905 | ||
A0A674G895 | A0A674G895_TAEGU | ATP2C1 | 907 | ||
A0A674GZA4 | A0A674GZA4_TAEGU | ATP2C1 | 840 |
Keywords
- Technical term