A0A674GBU4 · A0A674GBU4_TAEGU
- ProteinCysteine dioxygenase
- GeneCDO1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids203 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.
Catalytic activity
- L-cysteine + O2 = 3-sulfino-L-alanine + H+This reaction proceeds in the forward direction.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Fe cation per subunit.
Pathway
Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 88 | Fe cation (UniProtKB | ChEBI); catalytic | |||
Binding site | 90 | Fe cation (UniProtKB | ChEBI); catalytic | |||
Binding site | 143 | Fe cation (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | cysteine dioxygenase activity | |
Molecular Function | ferrous iron binding | |
Biological Process | L-cysteine catabolic process | |
Biological Process | taurine biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCysteine dioxygenase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia
Accessions
- Primary accessionA0A674GBU4
Proteomes
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Cross-link | 95↔160 | 3'-(S-cysteinyl)-tyrosine (Cys-Tyr) | |||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length203
- Mass (Da)23,543
- Last updated2020-06-17 v1
- Checksum84AF8DE964098BA9
Keywords
- Technical term