A0A674GAY5 · A0A674GAY5_TAEGU
- ProteinHistone acetyltransferase
- GeneKAT6A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1892 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-lysyl-[protein] + acetyl-CoA = N6-acetyl-L-lysyl-[protein] + CoA + H+
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 679 | Proton donor/acceptor | |||
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | MOZ/MORF histone acetyltransferase complex | |
Cellular Component | nucleosome | |
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | histone acetyltransferase activity | |
Molecular Function | metal ion binding | |
Molecular Function | transcription coregulator activity | |
Biological Process | negative regulation of DNA-templated transcription | |
Biological Process | nucleosome assembly | |
Biological Process | positive regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHistone acetyltransferase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia
Accessions
- Primary accessionA0A674GAY5
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-77 | SAMD1-like winged helix (WH) | |||
Domain | 95-171 | H15 | |||
Domain | 207-266 | PHD-type | |||
Domain | 263-314 | PHD-type | |||
Region | 336-377 | Disordered | |||
Compositional bias | 340-355 | Polar residues | |||
Region | 441-461 | Disordered | |||
Domain | 503-756 | MYST-type HAT | |||
Region | 739-759 | Disordered | |||
Compositional bias | 816-832 | Basic and acidic residues | |||
Region | 816-863 | Disordered | |||
Compositional bias | 846-863 | Basic and acidic residues | |||
Region | 897-1093 | Disordered | |||
Compositional bias | 925-943 | Basic residues | |||
Compositional bias | 978-998 | Acidic residues | |||
Compositional bias | 1013-1034 | Basic and acidic residues | |||
Compositional bias | 1064-1086 | Basic residues | |||
Compositional bias | 1109-1144 | Basic and acidic residues | |||
Region | 1109-1337 | Disordered | |||
Compositional bias | 1201-1216 | Acidic residues | |||
Compositional bias | 1237-1262 | Basic and acidic residues | |||
Compositional bias | 1304-1336 | Basic and acidic residues | |||
Region | 1390-1454 | Disordered | |||
Compositional bias | 1551-1574 | Polar residues | |||
Region | 1551-1610 | Disordered | |||
Compositional bias | 1575-1590 | Pro residues | |||
Sequence similarities
Belongs to the MYST (SAS/MOZ) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,892
- Mass (Da)212,022
- Last updated2020-06-17 v1
- ChecksumF3D6F3D8DB93DE0B
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
H0Z4T5 | H0Z4T5_TAEGU | KAT6A | 2015 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 340-355 | Polar residues | |||
Compositional bias | 816-832 | Basic and acidic residues | |||
Compositional bias | 846-863 | Basic and acidic residues | |||
Compositional bias | 925-943 | Basic residues | |||
Compositional bias | 978-998 | Acidic residues | |||
Compositional bias | 1013-1034 | Basic and acidic residues | |||
Compositional bias | 1064-1086 | Basic residues | |||
Compositional bias | 1109-1144 | Basic and acidic residues | |||
Compositional bias | 1201-1216 | Acidic residues | |||
Compositional bias | 1237-1262 | Basic and acidic residues | |||
Compositional bias | 1304-1336 | Basic and acidic residues | |||
Compositional bias | 1551-1574 | Polar residues | |||
Compositional bias | 1575-1590 | Pro residues | |||
Keywords
- Technical term