A0A674C4T9 · A0A674C4T9_SALTR

  • Protein
    RAF proto-oncogene serine/threonine-protein kinase
  • Gene
    raf1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site279ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionprotein serine/threonine kinase activity
Biological ProcessRas protein signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RAF proto-oncogene serine/threonine-protein kinase
  • EC number
  • Alternative names
    • Raf-1

Gene names

    • Name
      raf1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Salmo

Accessions

  • Primary accession
    A0A674C4T9

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-21Disordered
Domain23-96RBD
Domain103-149Phorbol-ester/DAG-type
Domain253-513Protein kinase
Domain439-507Cyclic nucleotide-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    546
  • Mass (Da)
    61,869
  • Last updated
    2020-06-17 v1
  • Checksum
    1FA3327950633AEB
MKGFPYQRRSSDDGKMADPKTSSTIRVYLPNKQCTVVNARPGMTLHNCLIKAMKVRGLQPECCAVFRLHSAQRKSRMDWNTDATSLIGEELLVDVLDHVPLTTHNFVRNTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLHSTLHAFNQAPGSLLGAGPAVLSHRLRSTSTPNVHMVSTTLPLDSTAFKSPSDLSLTCWSQTQSVSSRAPAPMHKERADKRASSYYWEIEASEVVLQNRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTEDNLAIVTQWCDGSSLYHHLHIQETNLQMFQLMDIARQTAQGMNYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSYQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGVVLYELMTGELPYSMIATRDQIIFMVGRGSLFPELSKLYKNCPKAMKRLVADCIKKSKDDRPLFPQILSSIELLQHALPRINRSTSEPSLHRATHTEDINILHKVPF

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A674C6H6A0A674C6H6_SALTRraf1664
A0A674C5V5A0A674C5V5_SALTRraf1614
A0A674C5V6A0A674C5V6_SALTRraf1320
A0A674C691A0A674C691_SALTRraf1596
A0A674C4U0A0A674C4U0_SALTRraf1647
A0A674C4V5A0A674C4V5_SALTRraf1640
A0A674C5P9A0A674C5P9_SALTRraf1637
A0A674C5J4A0A674C5J4_SALTRraf1608

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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