A0A671LB45 · A0A671LB45_9TELE
- ProteinPhosphatidylinositol-3,5-bisphosphate 3-phosphatase
- GeneLOC107661737
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids594 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 285-288 | substrate | ||||
Sequence: NKAK | ||||||
Active site | 372 | Phosphocysteine intermediate | ||||
Sequence: C | ||||||
Binding site | 372-378 | substrate | ||||
Sequence: CSDGWDR |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | |
Molecular Function | phosphatidylinositol-3-phosphate phosphatase activity | |
Biological Process | lipid metabolic process |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphatidylinositol-3,5-bisphosphate 3-phosphatase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Cyprinidae > Cyprininae > Sinocyclocheilus
Accessions
- Primary accessionA0A671LB45
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-18 | |||||
Sequence: MFFFFSVSSITALPSVFT | ||||||
Chain | PRO_5025451365 | 19-594 | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase | |||
Sequence: TSNVGLTVCFRRRENLKFGSGIKDVMYICPFSGVLRGTLTITDYKLFFKSLTRDPPFVLDVNLGAISRLESIAVQSHGDNTQGLEIVCKDLRNPRFAYKKEGQSNLEVFETLSKYTCPLSHNLPLFAFKYRETFPEDGWKIYDPVAEYKRSLFWYYVLMYLWIISKVNSSYKLCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCSQPQVGPSDRRCREDERYLQTILDANAQSHKLCIFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNMHVMRESLRKLKEVVYPAIDQQRWFSSVDSTHWLEYIRLLLAGAVRIADRIESGKTSAVVHCSDGWDRTAQLTSLAMLMLDAHYRSLRGFQVLLEKEWLSFGHRFASQVGHGDGNHANSERSPLFVQFIDCVWQMARQFPSAFEFNELFLITVLDHLYSCLFGTFLYNSEQERVSKEVYSKTVSLWSYVNSQLEEFTNPLYVNYEHHVLYPVASLRHLELWVSYYVRWNPRMRPQVPVHQSLKELLVLKSELQKRVDELKRDAASSHSLSSSSEHEGMPMQTTV |
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 156-535 | Myotubularin phosphatase | ||||
Sequence: GWKIYDPVAEYKRSLFWYYVLMYLWIISKVNSSYKLCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCSQPQVGPSDRRCREDERYLQTILDANAQSHKLCIFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNMHVMRESLRKLKEVVYPAIDQQRWFSSVDSTHWLEYIRLLLAGAVRIADRIESGKTSAVVHCSDGWDRTAQLTSLAMLMLDAHYRSLRGFQVLLEKEWLSFGHRFASQVGHGDGNHANSERSPLFVQFIDCVWQMARQFPSAFEFNELFLITVLDHLYSCLFGTFLYNSEQERVSKEVYSKTVSLWSYVNSQLEEFTNPLYVNYEHHVLYPVASLRHLELWVSYY | ||||||
Region | 572-594 | Disordered | ||||
Sequence: DAASSHSLSSSSEHEGMPMQTTV | ||||||
Compositional bias | 575-594 | Polar residues | ||||
Sequence: SSHSLSSSSEHEGMPMQTTV |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length594
- Mass (Da)68,776
- Last updated2020-06-17 v1
- Checksum70CC02C64FF4F74F
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A671LAS1 | A0A671LAS1_9TELE | LOC107661737 | 650 | ||
A0A671LDA1 | A0A671LDA1_9TELE | LOC107661737 | 646 | ||
A0A671LDI6 | A0A671LDI6_9TELE | LOC107661737 | 641 | ||
A0A671LCI1 | A0A671LCI1_9TELE | LOC107661737 | 513 | ||
A0A671LAG8 | A0A671LAG8_9TELE | LOC107661737 | 547 | ||
A0A671LAI7 | A0A671LAI7_9TELE | LOC107661737 | 543 | ||
A0A671LAK6 | A0A671LAK6_9TELE | LOC107661737 | 580 | ||
A0A671LAQ2 | A0A671LAQ2_9TELE | LOC107661737 | 629 | ||
A0A671LAB2 | A0A671LAB2_9TELE | LOC107661737 | 649 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 575-594 | Polar residues | ||||
Sequence: SSHSLSSSSEHEGMPMQTTV |
Keywords
- Technical term