A0A671EUY4 · A0A671EUY4_RHIFE

Function

Catalytic activity

  • (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • N-(9Z-octadecenoyl)-ethanolamine phosphate + H2O = N-(9Z-octadecenoyl) ethanolamine + phosphate
    This reaction proceeds in the forward direction.
  • N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphate
    This reaction proceeds in the forward direction.
  • a monoacyl-sn-glycero-3-phosphate + H2O = a monoacylglycerol + phosphate
    This reaction proceeds in the forward direction.
  • sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphate
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
    EC:3.1.3.4 (UniProtKB | ENZYME | Rhea)
  • a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:3.6.1.75 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
    EC:3.1.3.106 (UniProtKB | ENZYME | Rhea)
  • an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphate
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; phospholipid metabolism.
Phospholipid metabolism.

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcaveola
Molecular Functionlysophosphatidic acid phosphatase activity
Molecular Functionphosphatidate phosphatase activity
Biological Processphospholipid dephosphorylation
Biological Processphospholipid metabolic process
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipid phosphatase 1
  • EC number
  • Alternative names
    • Lipid phosphate phosphohydrolase 1
    • PAP2-alpha
    • Phosphatidate phosphohydrolase type 2a
    • Phosphatidic acid phosphatase 2a

Gene names

    • Name
      PLPP1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yinpterochiroptera > Rhinolophoidea > Rhinolophidae > Rhinolophinae > Rhinolophus

Accessions

  • Primary accession
    A0A671EUY4

Proteomes

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Membrane raft
; Multi-pass membrane protein
Membrane, caveola
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-27Helical
Transmembrane56-81Helical
Transmembrane93-111Helical
Transmembrane165-185Helical
Transmembrane197-216Helical
Transmembrane228-250Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Forms functional homodimers and homooligomers that are not required for substrate recognition and catalytic activity. Can also form heterooligomers with PLPP2 and PLPP3.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain102-243Phosphatidic acid phosphatase type 2/haloperoxidase
Region257-296Disordered
Compositional bias270-296Polar residues

Sequence similarities

Belongs to the PA-phosphatase related phosphoesterase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    296
  • Mass (Da)
    33,463
  • Last updated
    2020-06-17 v1
  • Checksum
    92DDDEE6CE31F3CF
MFDKTRLPYVALDVLCLLLAGLPFAILTSRHTPFQRGLFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVMIIGETLSVYCNVLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIENYICRGNAQKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKADWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERNSPFKERKEEDSHTTLHETPTTTTMTTTTTTTTGNHYRNNHQP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A671EZW6A0A671EZW6_RHIFEPLPP1297

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias270-296Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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