A0A671EUY4 · A0A671EUY4_RHIFE
- ProteinPhospholipid phosphatase 1
- GenePLPP1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids296 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphateThis reaction proceeds in the forward direction.
- N-(9Z-octadecenoyl)-ethanolamine phosphate + H2O = N-(9Z-octadecenoyl) ethanolamine + phosphateThis reaction proceeds in the forward direction.
- N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphateThis reaction proceeds in the forward direction.
- a monoacyl-sn-glycero-3-phosphate + H2O = a monoacylglycerol + phosphateThis reaction proceeds in the forward direction.
- sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphateThis reaction proceeds in the forward direction.
- an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphateThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism; phospholipid metabolism.
Phospholipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | caveola | |
Molecular Function | lysophosphatidic acid phosphatase activity | |
Molecular Function | phosphatidate phosphatase activity | |
Biological Process | phospholipid dephosphorylation | |
Biological Process | phospholipid metabolic process | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhospholipid phosphatase 1
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yinpterochiroptera > Rhinolophoidea > Rhinolophidae > Rhinolophinae > Rhinolophus
Accessions
- Primary accessionA0A671EUY4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Membrane raft ; Multi-pass membrane protein
Membrane, caveola ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 7-27 | Helical | |||
Transmembrane | 56-81 | Helical | |||
Transmembrane | 93-111 | Helical | |||
Transmembrane | 165-185 | Helical | |||
Transmembrane | 197-216 | Helical | |||
Transmembrane | 228-250 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Forms functional homodimers and homooligomers that are not required for substrate recognition and catalytic activity. Can also form heterooligomers with PLPP2 and PLPP3.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 102-243 | Phosphatidic acid phosphatase type 2/haloperoxidase | |||
Region | 257-296 | Disordered | |||
Compositional bias | 270-296 | Polar residues | |||
Sequence similarities
Belongs to the PA-phosphatase related phosphoesterase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length296
- Mass (Da)33,463
- Last updated2020-06-17 v1
- Checksum92DDDEE6CE31F3CF
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A671EZW6 | A0A671EZW6_RHIFE | PLPP1 | 297 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 270-296 | Polar residues | |||
Keywords
- Technical term