A0A668UH26 · A0A668UH26_OREAU

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Pathway

Amino-acid biosynthesis; beta-alanine biosynthesis.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functiondihydropyrimidine dehydrogenase (NADP+) activity
Molecular Functionmetal ion binding
Molecular FunctionNADP binding
Molecular Functionuracil binding
Biological Processbeta-alanine biosynthetic process
Biological Processthymine catabolic process
Biological Processuracil catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihydropyrimidine dehydrogenase [NADP(+)]
  • EC number
  • Alternative names
    • Dihydrothymine dehydrogenase
    • Dihydrouracil dehydrogenase

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Cichlomorphae > Cichliformes > Cichlidae > African cichlids > Pseudocrenilabrinae > Oreochromini > Oreochromis

Accessions

  • Primary accession
    A0A668UH26

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-38Dihydroprymidine dehydrogenase
Domain78-238FAD/NAD(P)-binding
Domain277-582Dihydroorotate dehydrogenase catalytic

Sequence similarities

Belongs to the dihydropyrimidine dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    623
  • Mass (Da)
    67,430
  • Last updated
    2020-06-17 v1
  • Checksum
    8CDD264FA0608F8E
TTLSERGALREALRCLKCADAPCQKSCPTNLDIKSFITIYVVLSLSPRLFACSPILGSLSLCLGMCQCRSSLPELKGVVIVLGAGDTAFDCATSALRCGAKRVYVCFRRGFTNIRAVPEEMELAKEEQCEFLPFLSPREVIMKNGHVAGLQFCRTEQTKEGDWVEDEEQIVRLKADYIISAFGSMLNEPQVTEAMTPVKLSRWGTPEVNTDTMQTSEPWVFAGGDIAGLANTTVESVNDGKQASWHIHRYIQSLHGQTIDPVPKLPLFYSAIDQVDLSIEVCGIKFPNPFGLASAPPTTSTAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVRGTTSGPLYGPGLGSFLNIELISEKTAAYWCQSVAELKKDFPNNVVISSIMCGYNKEDWTELAKMAEESGADALELNLSCPHGMGERGMGLACGQDPVLVRNICRWVREAISIPFFAKLTPNVTNIVDIAKAAHEGGADGVTATNTVSGLMGLKADGSPWPSVGLEKRTTYGGISGNAIRPITLRAVSAIARAIPGFPILATGGIDSAESGLQFLHAGASLLQVCSAVQNQDFTLIEDYCVGLKALLYLKSLELKDWDGQSPPTERHQKGKPAPRLESLVGKVQLQQL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A668UGV5A0A668UGV5_OREAU657

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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