A0A665T805 · A0A665T805_ECHNA
- ProteinProtein-glutamine gamma-glutamyltransferase 2
- GeneLOC115043419
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids677 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- L-glutaminyl-[protein] + (R)-noradrenaline = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + dopamine = 5-dopaminyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
- L-glutaminyl-[protein] + histamine = 5-histaminyl-L-glutamyl-[protein] + NH4+This reaction proceeds in the forward direction.
Cofactor
Note: Binds 1 Ca2+ ion per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 269 | ||||
Active site | 325 | ||||
Active site | 348 | ||||
Binding site | 388 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 390 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 436 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 441 | Ca2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome | |
Cellular Component | collagen-containing extracellular matrix | |
Cellular Component | cytosol | |
Cellular Component | extracellular region | |
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | GTP binding | |
Molecular Function | metal ion binding | |
Molecular Function | peptidase activity | |
Molecular Function | protein-glutamine gamma-glutamyltransferase activity | |
Biological Process | nervous system development | |
Biological Process | peptide cross-linking | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-glutamine gamma-glutamyltransferase 2
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Carangaria > Carangiformes > Echeneidae > Echeneis
Accessions
- Primary accessionA0A665T805
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length677
- Mass (Da)75,623
- Last updated2020-06-17 v1
- Checksum7B5880C5531266A2
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A665SXR5 | A0A665SXR5_ECHNA | LOC115043419 | 1241 | ||
A0A665T5I3 | A0A665T5I3_ECHNA | LOC115043419 | 683 | ||
A0A665T5I7 | A0A665T5I7_ECHNA | LOC115043419 | 692 | ||
A0A665SXB9 | A0A665SXB9_ECHNA | LOC115043419 | 691 | ||
A0A665SX89 | A0A665SX89_ECHNA | LOC115043419 | 653 | ||
A0A665SYC2 | A0A665SYC2_ECHNA | LOC115043419 | 653 | ||
A0A665T853 | A0A665T853_ECHNA | LOC115043419 | 678 | ||
A0A665TGX2 | A0A665TGX2_ECHNA | LOC115043419 | 673 | ||
A0A665TGU4 | A0A665TGU4_ECHNA | LOC115043419 | 667 |
Keywords
- Technical term