A0A654EM62 · A0A654EM62_ARATH

Function

Catalytic activity

Cofactor

Ni cation (UniProtKB | Rhea| CHEBI:25516 )

Note: Binds 2 nickel ions per subunit.

Pathway

Nitrogen metabolism; urea degradation; CO2 and NH3 from urea (urease route): step 1/1.

Features

Showing features for binding site, active site.

1838100200300400500600700800
Type
IDPosition(s)Description
Binding site405Ni2+ 1 (UniProtKB | ChEBI)
Binding site407Ni2+ 1 (UniProtKB | ChEBI)
Binding site488Ni2+ 2 (UniProtKB | ChEBI); via carbamate group
Binding site488Ni2+ 1 (UniProtKB | ChEBI); via carbamate group
Binding site490substrate
Binding site517Ni2+ 2 (UniProtKB | ChEBI)
Binding site543Ni2+ 2 (UniProtKB | ChEBI)
Active site591Proton donor
Binding site631Ni2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componenturease complex
Molecular Functionnickel cation binding
Molecular Functionurease activity
Biological Processurea catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Urease
  • EC number
  • Alternative names
    • Urea amidohydrolase

Gene names

    • ORF names
      AN1_LOCUS5764

Organism names

  • Taxonomic identifier
  • Strain
    • cv. An-1
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A654EM62

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue488N6-carboxylysine

Post-translational modification

Carbamylation allows a single lysine to coordinate two nickel ions.

Expression

Gene expression databases

Interaction

Subunit

Homohexamer. Other oligomeric forms may exist depending on pH and presence of salts.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain400-838Urease

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    838
  • Mass (Da)
    91,036
  • Last updated
    2020-04-22 v1
  • MD5 Checksum
    86D1DA98D13A67F3E9C2E7B639D30F49
MKLLPREIEKLELHQAGFLAQKRLARGIRLNYTEAVALIATQILEFIRDGEKSVAELMDIGRQLLGRRQVLPAVLHLLYTVQVEGTFRDGTKLVTVHEPISLENGNLELALHGSFLPVPSLDKFPEVHEGVIIPGDMKYGDGSIIINHGRKAVVLKVVNTGDRPVQVGSHYHFIEVNPLLVFDRRKALGMRLNIPAGTAVRFEPGERKSVVLVNIGGNKVIRGGNGIVDGLVDDVNWTVLMETMERRGFKHLEDVDASEGLAGEDPRFTTTISREKYANMYGPTTGDKLRLGDTNLYARIEKDYTVYGDECVFGGGKVLREGMGQGIEQAEALSLDTVITNSVIIDYSGIYKADIGIKNGHIVGIGKAGNPDTMHGVQNNMLIGNKTEVIAGEGMIVTAGAIDCHVHFICPQLVYEAVSSGITTMVGGGTGPAYGTRATTCTPSPFDMKLMLQSTDSLPLNFGFTGKGNTAKPLELRHILEAGAMGLKLHEDWGTTPAAIDNCLAVAEEYDIQVNIHTDTLNESGFVEHTINAFRGRTIHTYHSEGAGGGHAPDIIRVCGVKNVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDKNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVISRTWQTADKMKAQRGAIDPNMADDDNSRIKRYIAKYTINPAIANGFADLIGSVEVKKLADLVIWQPAFFGAKPEMIIKGGNIAWANMGDANASIPTPEPVISRPMFGAFGKAGSENSVAFVSKAALRKGVRELYGLKKRVVAVSNVRQLTKLDMKLNDALPEITVDPETYVVTANGEVLTCAPADSVPLSRNYFLF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CACRSJ010000104
EMBL· GenBank· DDBJ
VYS50294.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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