A0A654EM62 · A0A654EM62_ARATH
- ProteinUrease
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids838 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- urea + 2 H2O + H+ = hydrogencarbonate + 2 NH4+
Cofactor
Note: Binds 2 nickel ions per subunit.
Pathway
Nitrogen metabolism; urea degradation; CO2 and NH3 from urea (urease route): step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 405 | Ni2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 407 | Ni2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 488 | Ni2+ 2 (UniProtKB | ChEBI); via carbamate group | |||
Binding site | 488 | Ni2+ 1 (UniProtKB | ChEBI); via carbamate group | |||
Binding site | 490 | substrate | |||
Binding site | 517 | Ni2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 543 | Ni2+ 2 (UniProtKB | ChEBI) | |||
Active site | 591 | Proton donor | |||
Binding site | 631 | Ni2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | urease complex | |
Molecular Function | nickel cation binding | |
Molecular Function | urease activity | |
Biological Process | urea catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUrease
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A654EM62
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 488 | N6-carboxylysine | |||
Post-translational modification
Carbamylation allows a single lysine to coordinate two nickel ions.
Expression
Gene expression databases
Interaction
Subunit
Homohexamer. Other oligomeric forms may exist depending on pH and presence of salts.
Structure
Sequence
- Sequence statusComplete
- Length838
- Mass (Da)91,036
- Last updated2020-04-22 v1
- MD5 Checksum86D1DA98D13A67F3E9C2E7B639D30F49
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CACRSJ010000104 EMBL· GenBank· DDBJ | VYS50294.1 EMBL· GenBank· DDBJ | Genomic DNA |