A0A650F360 · A0A650F360_9EUCA
- ProteinNADH-ubiquinone oxidoreductase chain 1
- Genenad1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids312 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Catalytic activity
- a ubiquinone + NADH + 5 H+(in) = a ubiquinol + NAD+ + 4 H+(out)
a ubiquinone RHEA-COMP:9565 + CHEBI:57945 + 5 H+ (in)CHEBI:15378= a ubiquinol RHEA-COMP:9566 + CHEBI:57540 + 4 H+ (out)CHEBI:15378
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Biological Process | aerobic respiration |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH-ubiquinone oxidoreductase chain 1
- EC number
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Multicrustacea > Malacostraca > Eumalacostraca > Eucarida > Decapoda > Pleocyemata > Brachyura > Eubrachyura > Potamoidea > Potamidae > Tenuipotamon
Accessions
- Primary accessionA0A650F360
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Mitochondrion membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-26 | Helical | |||
Transmembrane | 71-92 | Helical | |||
Transmembrane | 98-122 | Helical | |||
Transmembrane | 143-163 | Helical | |||
Transmembrane | 175-194 | Helical | |||
Transmembrane | 223-247 | Helical | |||
Transmembrane | 253-269 | Helical | |||
Transmembrane | 289-311 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length312
- Mass (Da)35,278
- Last updated2020-04-22 v1
- Checksum7A5F6A95CEFA2632
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MN737140 EMBL· GenBank· DDBJ | QGT77321.1 EMBL· GenBank· DDBJ | Genomic DNA |