A0A641AHJ3 · A0A641AHJ3_9ACTN

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site12ADP (UniProtKB | ChEBI)
Binding site12ATP (UniProtKB | ChEBI)
Binding site12sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site16ADP (UniProtKB | ChEBI)
Binding site82glycerol (UniProtKB | ChEBI)
Binding site82sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site83glycerol (UniProtKB | ChEBI)
Binding site83sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site134glycerol (UniProtKB | ChEBI)
Binding site134sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site247glycerol (UniProtKB | ChEBI)
Binding site247sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site248glycerol (UniProtKB | ChEBI)
Binding site269ADP (UniProtKB | ChEBI)
Binding site269ATP (UniProtKB | ChEBI)
Binding site313ADP (UniProtKB | ChEBI)
Binding site313ATP (UniProtKB | ChEBI)
Binding site317ATP (UniProtKB | ChEBI)
Binding site414ADP (UniProtKB | ChEBI)
Binding site414ATP (UniProtKB | ChEBI)
Binding site418ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      ESP62_016620

Organism names

  • Taxonomic identifier
  • Strain
    • NRBC 14897
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Nocardioidaceae > Aeromicrobium

Accessions

  • Primary accession
    A0A641AHJ3

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-254Carbohydrate kinase FGGY N-terminal
Domain264-453Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    503
  • Mass (Da)
    54,562
  • Last updated
    2020-04-22 v1
  • Checksum
    91B77867ABEDD9D2
MAKYVGAIDQGTTSTRFMIFDHDGHEVARHQLEHEQIMPEAGWVEHDPHEIWEATQDVVQTAMGRAGITADDLAAIGITNQRETTVVWDRRTGEPYYNAIVWQDTRTDRIASALERDGHADLICRRSGLPPAPYFAGGKLQWILENVDGVRADADAGHAIFGTIDTWLIWWLTGGPDDGLHMTDVTNASRTMLMDLETLAWDDELLAIFDVPRSMLPEIRSSSEVYGSTEAEGPFSGEVRIAGDLGDQHAALVGQVCFEPGQLKNTYGTGNFLVLNTGTEIVRSTHGLLTTVAYQLGDAPAVYALEGSIAVTGSAIQWLRDQLGIIRAAGDSEALAASVDDNGGVSFVPAFSGLFAPYWRSDARGVIAGLSRYNTGAHVARAALEAICYQSRDVVDAMVADADLDLQILRVDGGVTANELCMQIQADVLGVPVSRPVVAETTALGSAYAAGLAVGFWASTDELVANWNESRRWESTSTQEQRDAGHAQWKKAVERTMGWVEVD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SDPP02000005
EMBL· GenBank· DDBJ
KAA1373586.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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