A0A640NFV6 · A0A640NFV6_BACAN
- ProteinMultifunctional fusion protein
- GenemsrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids321 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Catalytic activity
- [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:57844 + CHEBI:15377 = CHEBI:58772 + RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 16 | ||||
Active site | 291 | Nucleophile | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | peptide-methionine (R)-S-oxide reductase activity | |
Molecular Function | peptide-methionine (S)-S-oxide reductase activity | |
Biological Process | protein modification process | |
Biological Process | protein repair | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended namePeptide methionine sulfoxide reductase MsrA
- EC number
- Short namesProtein-methionine-S-oxide reductase
- Alternative names
- Recommended namePeptide methionine sulfoxide reductase MsrB
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus cereus group
Accessions
- Primary accessionA0A640NFV6
- Secondary accessions
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 180-302 | MsrB | |||
Sequence similarities
Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length321
- Mass (Da)36,727
- Last updated2020-04-22 v1
- ChecksumC4DB14C6957CB7DB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BLET01000030 EMBL· GenBank· DDBJ | GET95355.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BLEU01000006 EMBL· GenBank· DDBJ | GEU02155.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BLEV01000004 EMBL· GenBank· DDBJ | GEU08038.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BLEX01000007 EMBL· GenBank· DDBJ | GEU15693.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BLEW01000013 EMBL· GenBank· DDBJ | GEU24690.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BLEY01000005 EMBL· GenBank· DDBJ | GEU24811.1 EMBL· GenBank· DDBJ | Genomic DNA |