A0A609W3P9 · A0A609W3P9_SALET

Function

function

A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell outer membrane
Cellular Componentextracellular region
Molecular Functionlipid binding
Molecular Functionpeptidoglycan binding
Biological Processlipid modification
Biological Processperiplasmic space organization

Names & Taxonomy

Protein names

  • Recommended name
    Major outer membrane lipoprotein Lpp
  • Alternative names
    • Braun lipoprotein
    • Murein lipoprotein
      (BLP
      )

Gene names

    • Name
      lpp
    • ORF names
      CIL65_07280

Organism names

Accessions

  • Primary accession
    A0A609W3P9

Subcellular Location

Cell outer membrane
; Lipid-anchor
Secreted, cell wall
; Peptidoglycan-anchor
Note: Attached via its lipidated N-terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.

Keywords

PTM/Processing

Features

Showing features for signal, lipidation, chain, modified residue.

Type
IDPosition(s)Description
Signal1-26
Lipidation22N-palmitoyl cysteine
Lipidation22S-diacylglycerol cysteine
ChainPRO_502613808127-80Major outer membrane lipoprotein Lpp
Modified residue80N6-murein peptidoglycan lysine

Keywords

Interaction

Subunit

Homotrimer.

Family & Domains

Features

Showing features for domain, repeat, region.

Type
IDPosition(s)Description
Domain27-76Lipoprotein leucine-zipper
Repeat39-49
Region59-80Disordered

Sequence similarities

Belongs to the Lpp family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    80
  • Mass (Da)
    8,523
  • Last updated
    2020-08-12 v1
  • MD5 Checksum
    6BBCB883C5F40AE95B6F831D94636C54
MNRTNKLILGAAVLGSTLLAGCSSNAKIDQLSSDVQTLSAKVEQLSNDVNAMRSDVQAAKDDAARANQRLDNKVVSHVRK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAKTKA010000010
EMBL· GenBank· DDBJ
ECV4805693.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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