A0A5V6UH73 · A0A5V6UH73_SALTM

  • Protein
    Anthranilate phosphoribosyltransferase
  • Gene
    trpD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site84Nucleophile
Active site170
Active site172
Binding site2785-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site278anthranilate 1 (UniProtKB | ChEBI)
Binding site281-2825-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site2865-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site288-2915-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site290Mg2+ 1 (UniProtKB | ChEBI)
Binding site306-3145-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site309anthranilate 1 (UniProtKB | ChEBI)
Binding site3185-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site364anthranilate 2 (UniProtKB | ChEBI)
Binding site422Mg2+ 2 (UniProtKB | ChEBI)
Binding site423Mg2+ 1 (UniProtKB | ChEBI)
Binding site423Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionlyase activity
Molecular Functionmagnesium ion binding
Biological Processglutamine metabolic process
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • Synonyms
      trpGD
    • ORF names
      CC453_16040
      , CQO33_05145
      , DLR28_07065
      , G0C04_01275
      , G0J24_01250
      , G0J26_00180
      , G0J27_05095
      , G0J28_00190
      , G0J31_01800
      , G0J33_05585
      , G0J34_01250
      , G0J36_00195
      , G0J37_01250
      , G0J40_00195
      , G0J44_00195
      , G0J45_00195
      , G0J46_00765
      , G0J47_01250
      , G0J49_01240
      , G0J51_00185
      , G0J55_00765
      , G0J62_16520
      , G0K00_00190
      , G0K03_00195
      , G0K15_00795
      , G0K23_00185
      , G0K47_01235
      , G0L31_18465
      , G0L36_21495
      , G0L37_21865
      , G3V21_002160
      , G4O69_000245
      , H8S97_08845
      , JJB80_08865
      , JJB81_08860
      , STMLT2P22_CBEKMEGD_02533

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 251833
    • 351313
    • 442688
    • IVB 232
    • L00535-14
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella

Accessions

  • Primary accession
    A0A5V6UH73

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-186Glutamine amidotransferase
Domain201-263Glycosyl transferase family 3 N-terminal
Domain272-521Glycosyl transferase family 3

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    531
  • Mass (Da)
    56,918
  • Last updated
    2020-04-22 v1
  • Checksum
    256D2409062CD4C7
MADILLLDNIDSFTWNLADQLRTNGHNVVIYRNHIPAQTLIDRLATMKNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAGEILHGKASSIEHDGQAMFAGLANPLPVARYHSLVGSNVPAGLTINAHFNGMVMAVRHDADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLTQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPEYLFADIVGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGLRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDFGLTPYHQDQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGQEDLKANAQTVLDVLRNGTAYDRVTALAARG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR881463
EMBL· GenBank· DDBJ
CAD5309087.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHDKE010000005
EMBL· GenBank· DDBJ
EBU8556909.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHHPX010000004
EMBL· GenBank· DDBJ
EBW1890936.1
EMBL· GenBank· DDBJ
Genomic DNA
AAMJIC010000045
EMBL· GenBank· DDBJ
EDH9460324.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAMGT010000001
EMBL· GenBank· DDBJ
HAC6591232.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAH010000020
EMBL· GenBank· DDBJ
HAC9001022.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAN010000001
EMBL· GenBank· DDBJ
HAC9010430.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAP010000001
EMBL· GenBank· DDBJ
HAC9019956.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAO010000002
EMBL· GenBank· DDBJ
HAC9025144.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAR010000004
EMBL· GenBank· DDBJ
HAC9035552.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAT010000001
EMBL· GenBank· DDBJ
HAC9039383.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAS010000001
EMBL· GenBank· DDBJ
HAC9044430.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAZ010000001
EMBL· GenBank· DDBJ
HAC9049101.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAU010000001
EMBL· GenBank· DDBJ
HAC9053968.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANAV010000001
EMBL· GenBank· DDBJ
HAC9068563.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBA010000001
EMBL· GenBank· DDBJ
HAC9078429.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBG010000001
EMBL· GenBank· DDBJ
HAC9107635.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBH010000001
EMBL· GenBank· DDBJ
HAC9117202.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBL010000001
EMBL· GenBank· DDBJ
HAC9131810.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBT010000098
EMBL· GenBank· DDBJ
HAC9169429.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBW010000001
EMBL· GenBank· DDBJ
HAC9181186.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANBZ010000001
EMBL· GenBank· DDBJ
HAC9195688.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANCC010000001
EMBL· GenBank· DDBJ
HAC9215316.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANDO010000001
EMBL· GenBank· DDBJ
HAC9399018.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANDS010000001
EMBL· GenBank· DDBJ
HAC9418417.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANDY010000001
EMBL· GenBank· DDBJ
HAC9442400.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANEL010000001
EMBL· GenBank· DDBJ
HAC9505448.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANFM010000001
EMBL· GenBank· DDBJ
HAC9640891.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANHR010000045
EMBL· GenBank· DDBJ
HAC9915278.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANHU010000064
EMBL· GenBank· DDBJ
HAC9934804.1
EMBL· GenBank· DDBJ
Genomic DNA
DAANIH010000073
EMBL· GenBank· DDBJ
HAC9990970.1
EMBL· GenBank· DDBJ
Genomic DNA
DAARCM010000032
EMBL· GenBank· DDBJ
HAE1857537.1
EMBL· GenBank· DDBJ
Genomic DNA
DAASWB010000001
EMBL· GenBank· DDBJ
HAE7264015.1
EMBL· GenBank· DDBJ
Genomic DNA
CP060507
EMBL· GenBank· DDBJ
QNL56444.1
EMBL· GenBank· DDBJ
Genomic DNA
CP067091
EMBL· GenBank· DDBJ
QTQ01395.1
EMBL· GenBank· DDBJ
Genomic DNA
CP067397
EMBL· GenBank· DDBJ
QTQ05911.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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