A0A5S9TS86 · A0A5S9TS86_ARATH

Function

Catalytic activity

  • Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.
    EC:5.6.2.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

115452004006008001,0001,2001,400
TypeIDPosition(s)Description
Binding site33ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular Functionhydrolase activity
Molecular Functionisomerase activity
Molecular Functionprotein kinase activity
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological ProcessDNA replication
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA 3'-5' helicase
  • EC number

Gene names

    • ORF names
      C24_LOCUS1100

Organism names

  • Taxonomic identifier
  • Strain
    • cv. C24
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A5S9TS86

Proteomes

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

Type
IDPosition(s)Description
Domain4-260Protein kinase
Region309-349Disordered
Compositional bias322-347Acidic residues
Coiled coil683-713
Domain832-1007Helicase ATP-binding
Domain1019-1164Helicase C-terminal
Region1345-1372Disordered
Compositional bias1350-1367Polar residues
Domain1375-1457HRDC
Region1459-1504Disordered
Compositional bias1466-1483Basic and acidic residues
Region1525-1545Disordered

Sequence similarities

Belongs to the helicase family. RecQ subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,545
  • Mass (Da)
    173,804
  • Last updated
    2020-04-22 v1
  • MD5 Checksum
    F6F7E0434ED61C9C3F6CB25ADD7EAA20
MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPRELTETAQAAYFKKENPTFSLQTVEEIMKIVADAKTPPPVSRSIGGFGWGGNGDADGKEEDAEDVEEEEEEVEEEEDDEDEYDKTVKEVHASGERENIPPLGNRIIFYGLELNRSHLPEVQKPRGPQTNWSEHAKALESSSSVTKFLSSNVLYALESQKPRDMAARSIAFPSVNVHTLAHPQISKAWRALSSLSVNNTYLRPGVTPPIDVGTNDSYSARERSTAKVISSTGGSVYSSTRPNLSAMNVSGTGRSFHSFPSSVPGDDKIVAEKFPRGNNEIRESEPSCTHLNGVEKSFGNSAFPAEQFESRKACLDDMDDDDILENIDVDQIVMEHYHSTSTPQPSVSNFSLRTPPVDRSASRLEEECNLPPELCSNCSHGIKLGLCPEASTHVEQMKDVLLAISNELLDDATDLSPDRVGQLRQERLRLKKQIQQLENHIRDKESQKSQFLSSTATRIFQYETPKSTNYKMDQPQTDFRAHVSDQGRYACDSWNTPRDSSFSVDRYGLSSAPVEREQYVPKIIDVTYTEGSNDKKWSSREFPWTRKLEVNNKKVFGNHSFRPNQREIINATMSGSDVFVLMPTGGGKSLTYQLPALICGGITLVISPLVSLIQDQIMNLLQANIPAASLSAGMEWAEQLKIFQELNSEHSKYKLLYVTPEKVAKSDSLLRHLENLNSRGLLARFVIDEAHCVSQWGHDFRPDYQSLGILKQKFPNIPVLALTATATASVKEDVNAAYQEVCRYSVVPKTKKCLEDIDKFIKENHFDECGIIYCLSRMDCEKVSERLQEFGHKAAFYHGSMEPEQRAFIQTQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYGYGDYIRVKHMISQGGVDQSPMATGYNRVASSGRLLETNTENLLRMVRYCENEVECRRFLQLVHLGEKFDSTNCKKTCDNCCSSQSLIDKDVTLITRQLVELVKQTGERFSSAHILEVYRGSLNQMVKKHRHETLQFHGAGKHLSKIEVSRILHYLVTEDILVEDVRKSDMYGSVSSLLKVNNAKATILFSGSQTIVMKFPSSVKVLKPSKQGATAAKGPLTSEKQSTLPLTTEDAPPKDVNLSANMYTALRKLRTALVKEAPDGVMAYHIFINSTLQQISRRIPRTKEELLEINGLGKAKVSKYGDQLLETIETTVNEYYGTNKKDSIISNDSPDSGKRRRDENISPNVAEDDDFEVSPSQSCKKTVRNKSNEVLHGECIDGDRRGMELDFDFKDEDGSEIRPEGRVLPW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias322-347Acidic residues
Compositional bias1350-1367Polar residues
Compositional bias1466-1483Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CACSHJ010000087
EMBL· GenBank· DDBJ
CAA0189397.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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