A0A5Q0TJW2 · A0A5Q0TJW2_LACLL
- ProteinGlutamate/gamma-aminobutyrate antiporter
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids503 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 4-aminobutanoate(in) + L-glutamate(out) = 4-aminobutanoate(out) + L-glutamate(in)4-aminobutanoate (in)CHEBI:59888
+ L-glutamate (out)CHEBI:29985= 4-aminobutanoate (out)CHEBI:59888+ L-glutamate (in)CHEBI:29985
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | transmembrane transporter activity | |
Biological Process | amino acid transport |
Names & Taxonomy
Protein names
- Recommended nameGlutamate/gamma-aminobutyrate antiporter
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus
Accessions
- Primary accessionA0A5Q0TJW2
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 37-59 | Helical | ||||
Sequence: FFLLLGGLLWFLPVALCAAEMAT | ||||||
Transmembrane | 80-109 | Helical | ||||
Sequence: FGFAAIFFQWFQITVGFVTMIYFILGALSY | ||||||
Transmembrane | 121-139 | Helical | ||||
Sequence: LIKFIGLLIIFWGLTFSQL | ||||||
Transmembrane | 151-173 | Helical | ||||
Sequence: AGFVVGIVIPSIILFGLAAAYFI | ||||||
Transmembrane | 193-210 | Helical | ||||
Sequence: QVSTLVVFVSFILAYMGV | ||||||
Transmembrane | 231-253 | Helical | ||||
Sequence: MILLVILAISLDAIGGFSVAAVI | ||||||
Transmembrane | 281-303 | Helical | ||||
Sequence: WLVKVIALMIAFGVMGEVSSWVV | ||||||
Transmembrane | 330-352 | Helical | ||||
Sequence: VPVPLVMIQGIIVTLWGAVLTFG | ||||||
Transmembrane | 358-385 | Helical | ||||
Sequence: LSFLVAISLTVVIYLVGYLLFFIGYFVL | ||||||
Transmembrane | 406-425 | Helical | ||||
Sequence: TIIAGIGFLLSIFALFISFV | ||||||
Transmembrane | 437-457 | Helical | ||||
Sequence: TYQMILLISFVVTAILPFIVY |
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length503
- Mass (Da)55,611
- Last updated2020-02-26 v1
- Checksum5714DB6B79CA5F57