A0A5Q0QME0 · A0A5Q0QME0_9RHAB

Function

Catalytic activity

  • GTP + H2O = GDP + phosphate + H+
  • a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-homocysteine + H+
    EC:2.1.1.375 (UniProtKB | ENZYME | Rhea)
  • a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine + H+
  • a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H+ = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate
    EC:2.7.7.88 (UniProtKB | ENZYME | Rhea)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell cytoplasm
Cellular Componentvirion component
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular FunctionmRNA 5'-cap (guanine-N7-)-methyltransferase activity
Molecular FunctionRNA-dependent RNA polymerase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      L
    • ORF names
      ADOKOPBE_00006

Organism names

  • Taxonomic identifier
  • Strains
    • Bolu/06
    • TR206239
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Gammarhabdovirinae > Novirhabdovirus > Novirhabdovirus piscine

Accessions

  • Primary accession
    A0A5Q0QME0

Subcellular Location

Keywords

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain560-757RdRp catalytic
Domain1589-1786Mononegavirus-type SAM-dependent 2'-O-MTase

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,984
  • Mass (Da)
    224,214
  • Last updated
    2020-02-26 v1
  • MD5 Checksum
    E326C7FF80D82FCB0124B01F3C29E77F
MEMFELDREVHQERLPSECSLNSPLNLSLSLQLFGRLVPKTEHIRYQAGRIKRWLARQYQLVHLKELEIDSTRIQGYLIPHLLKTQSNELGSSVIKNWGMVSKYYLSLGYTLPPKDKFEFREVAPYWNLASQLREVTLESQKVDARGKEKRKLYQVEDVEFEFKEGVVVIRAGPDGLLNEFLGGAKLGAVTYVEYLALFKIINQRAQALLLTAICQTLEPDLVPPCSGILSIYAEVDSVLRRAGQSAIDLLKLWEPLVLTKLGDVLGDRFGLENDFKDTIRGEANKLAKRLHVTRSYERMMRTLDQETRAQALFQYFGLFKHFAYPRVYSRETIEAIQEVSDKPSDSSPLNYLSDQCKIREEFYIRYTKAYHRAPAMNLGQLGQGSYLRQVLEAGKIPNTKNALYSLLEWFFVRFEKSIEWPLSDTLSTFLSDKAITQNRDIWYDGGSSGKDTTEKRLLLKFIKENEDSVEKVILKADEIYDKKADQIIALKVKEMELKIKGRGFGLMAFKPRLLQVLRESIAKKTSKLFPEITMTFSDLELKKKKFQLSRKSDDRRGYIHISKSLDINKFCTSQRQFNSLAVFQSLDELLGTDQLFTRVHEIFEKTWIVDGSASDPPDLVTFKARYEEALALGIEAPHVWADGAFSGLMGGIEGLCQYVWTICLLLRVERVLAVTQLTHFVMAQGDNVIINLIIPVEVDRVGGVVEGERARIQHISKGIDSALERELLRSGLTLKIEETLTSENLSIYGKDLHCPQHLTLAVKKAGSASIISSEQYQDVPTFLSGLGTGMETISECVNNKVSAHLFGVILGAAGWKSLAQRQTWKGWEYPFQNEATRRQVRSQGILLQKGESTMVHKEPEVNPEKRTIELLLVSSLFGSALGMLPFPTPIDLEKRGVGDYVTHRLSIVKMALVSKKLPNRMVEMIVSTMNLPLSREQDLTKLFDSPFSLNLATEEDAASVIKRLARGTLRGLDIKNKKLADHIATMDQGITQIDDALASADTINPRIAYQMRNITDQKESEMFVTKFATAKTMRMVALSSSQDVSVVGLLNKRSQAKEIYTIWRTQRKRETLWTCSTQQAKKLRDLSWGKNIIGVTSPSPLEATRFKLIDPISWEEEKEAHHFTIHYYLSKPSLSSKTAHTTRGPLVPYFGTQTKPLIAKAYMELKGNPRTNKALQLLSMRETMIKAGSNLDKLLLSLCSNALDIDVNSLPSLQAQEEASAGEGVRGGIKESMSPVGPDNLYTHITHKVFERQWLSEFHVNIADFIIWGITKTRQHLQVDTDLGGSLPICVPACPECYREKERAFLDIPREAEWVNTSTTSDKAQTYFSTWCDLPRVSTLPSLDQKDATCLMGRSMATQKSTPGESITKFYSTAPDTHRLLYPVTLVLGYAEGTIFSYMKSQHNIHGSLYHPHIDEIEPALEKYVIDTKTSHTKHLGYLFQDADSLQELLETGMTPYIPRSIPLTITELTSACCMTLAKAISIVLRTGVTIPLMPENGYGENDIQVARLTANSFSRLMPRGKIQLVYLDCDLTSQMTAWAPTSQPSVLGSVNFHIEGIAIPLTATEMRVGQESWEERKWTCSNNRHIIAKGVKTKSLFIHQSVPEIITHPPDLIVVIGGGLGGCVVPYLQKWKDPKVIFCTLFDERERISEDGDLIIPPELLVRGLAGRMVEKELLEAEMCDITVKGNRDLLIKVVQKWAQPNEHVLLIDEIENRGDQESVLQSSISELLTRMDSVCNLTSVHTIRETGPRQFAQRVNTIRRGRKTATLHWNQYNRRDQVEALLLIESHTRKTELHVTSSAVQAAFRKIDEKLESESRLEHSKWSLPELPPREKDILLGYVASVFLKLGLVVTDRHMSAAALITLLEEAGPKMISWDKKMEHRTWASSDAITEKGVTQDQIFSLLCFAWALRGLKSGDWEHNADAIILQDVHIDTGPRLCQMGESPKRTFASFRLHNTKKAEDLKGYLGALLHLESFFPFGEQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK829416
EMBL· GenBank· DDBJ
QGA30735.1
EMBL· GenBank· DDBJ
Viral cRNA
MN038332
EMBL· GenBank· DDBJ
QGR68827.1
EMBL· GenBank· DDBJ
Viral cRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help