A0A5Q0GSR8 · A0A5Q0GSR8_SACSY
- Proteinproline dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids307 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H+
Cofactor
Note: Binds 1 FAD per subunit.
Pathway
Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 98 | substrate | ||||
Sequence: K | ||||||
Binding site | 136 | FAD (UniProtKB | ChEBI) | ||||
Sequence: M | ||||||
Binding site | 164 | FAD (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 188-190 | FAD (UniProtKB | ChEBI) | ||||
Sequence: KGA | ||||||
Binding site | 202 | FAD (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 227-228 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SH | ||||||
Binding site | 287 | substrate | ||||
Sequence: R | ||||||
Binding site | 288 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleotide binding | |
Molecular Function | proline dehydrogenase activity | |
Biological Process | proline catabolic process to glutamate |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameproline dehydrogenase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Saccharothrix
Accessions
- Primary accessionA0A5Q0GSR8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 43-298 | Proline dehydrogenase | ||||
Sequence: ATTGELVADGRYVTLDHLGEDTRDADQAAATVEAYLDLLRRLELAGHTGRAEVSVKLSAVGQFLPEDGEKIALDNARRICAAAGAVGTTVTLDMEDHTTTDSTLGILRELRVDFPWVGAVLQAYLKRTEQDCRDLAGPGSRVRLCKGAYKEPASVAFQDKTEVDLSYVRCLKVLMAGRGYPMVASHDPRLIAIARELASGRSKDSYEFQMLYGIRPDEQRRLAAEGHRMRVYVPYGDQWYGYFMRRLAERPANVAF |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length307
- Mass (Da)33,972
- Last updated2020-04-22 v1
- ChecksumBAF487D9540CDDCE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP034550 EMBL· GenBank· DDBJ | QFZ17136.1 EMBL· GenBank· DDBJ | Genomic DNA |