A0A5P9K6L9 · A0A5P9K6L9_9NIDO

  • Protein
    Replicase polyprotein 1ab
  • Gene
    ORF1B
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for active site.

123412004006008001,0001,2001,4001,6001,8002,0002,200
TypeIDPosition(s)Description
Active site1457
Active site1459
Active site1560
Active site1633
Active site1638
Active site1947
Active site1964
Active site1998

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function3'-5'-RNA exonuclease activity
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular Functionendonuclease activity
Molecular FunctionmRNA (nucleoside-2'-O-)-methyltransferase activity
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription
Biological Processmethylation
Biological Processviral translational frameshifting

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Replicase polyprotein 1ab
  • Alternative names
    • ORF1ab polyprotein

Gene names

    • Name
      ORF1B

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • L4
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Pisuviricota > Pisoniviricetes > Nidovirales > Tornidovirineae > Tobaniviridae > Serpentovirinae

Accessions

  • Primary accession
    A0A5P9K6L9

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-18Polar residues
Region1-32Disordered
Domain46-275NiRAN
Domain884-972CV ZBD
Domain1430-1654ExoN
Domain1919-2053NendoU
Domain2069-2341Nidovirus-type SAM-dependent 2'-O-MTase

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,341
  • Mass (Da)
    266,091
  • Last updated
    2020-02-26 v1
  • Checksum
    41A2A02E00CF187F
MQLKPNKPSTQGKNNDACRQAPRNAPAGKKLVSSAVKQVTGDFELVSRQVSDILQKPDIYFGLRGDEQPDSKGRWVNVCQQDSGIKRLQKCRTISIEINHRNHMLKTGSEKSLRHEYNQYLVLKDSIAIPEHQLVKLDNGSYVLIRGPVSNDSLGDLVYSHFHNSNEEAPEIPDKGKPSAQAICDALAERLEPAFENLDRLRAWCLKYNVQLPITLDNIDMNGQLYDFEDINTSPHNIDIALSDFMRLWSLTNRPPPEVAKKWFPVKYNLHECSWLEKVLQVNNNLLHAKNTNTEIFIDASSNTTSMYHNDVTGTHTIDSEQLNSCSDFLQNLYYLQDPGLHWRKPVITVGNRVNFAATTDNHETPANRPVYYNEEAFNFFESRLGNIDSVLDYTYFQGDNANCVNDFLYYDYQGRLFLQPHLVKFLYERTRKDFSSCATDVRFSKLECTPRKSSLGPSHTLLRSYKQDQIYTAAPDNFIEELVNLSEQSALIFSTKCVQKFALTAKPRARTIAACSMTASTLFRALHKPVTANFVTQTQKQGTEIHHLIGVSKFRGGFHNWFTSRHGDISNWKVFGSDYTKCDRSFPLVFRSMAAALLFDLGGWDPHSHHFTNEMHAFMFDIVHLDGKLVYKPGGTSSGDATTAFANTLYNHGVHLLVQLQTLVTQQVHQNHLALKVAAVKGFQTGDFDDYNAMLDHYNKTQYKFNFLSDDSFILTNIHDKTLPDIYNKHNFSKHLETIIHTTVDQNKAWESEGDLHEFCSSTVKPCNGILQYIPDKHRLLAALCIEGKASTAELRVVRIAAILAEGVIYSQVDLNFWRVLWEYFENQLAEFIEQYGVLPIPDKMTEAEFYYGLIDPDKSPSDMELFQSVLADWGIKDVEMQAKNQVQQQCYTCHNPTVSTCIDCPVAYPLCCYCACTHYNETGHKVTHLPVCSHPGCGMSDPECMNFSLDNGQFTIRCDEHNTTFSIKVYDNKTQSFRLPLNQYCVKQESTVSNISKTIDNFTEGDFFSWNVEESKTSNMTRLLHESYLNDQYSAEQDIIFDYTVLDIKNNEVMIKDASYGLTTYCNILDSNGKIKLNCTVDPLRKDVYRLTFLDDTKRFINFDKIQRSNRVASKTDLSLLDVFKRTKFILGPPGTGKTTYFIENYFSKQRHNKVVYAAPTHKLVQDMDEALKGNSNVTVYKGKYNNREYHAPIDDESKPLVLCTVNIVRPIAGCVLLIDECSLLSPKQLFDAIIRSRAGEVICVGDPFQLSPVTPVTDFCWDYETFYLRQLVPQYNQTVLSTCYRCPRNIFNIFAGAYHNHNIEFNAAKEGGIVNWHRLKNDGIVISQKVLQEADNAGLDIVLVNYKQAAIDALNLKTRFVTIDSAQGLTVGKVGVIIFGSTKFSKVLNRLIVATSRATQQLDIWCCASVEDHIREHLCTKTVTPQALLTRPNCLTEIDIQTLASNIEATAVCDIEFYHAKHPTRSTPNFLGLGEINCLTSRSTTTFLRPHYNRDGDYLEVEDSYIRVSKEWKYMLRHLPNYVDSDMRRNHFLHFLNDTTNLSNSPLIFVLFNGTNDLDALAEITTPAGTCHCGKPARFTTNTDEDVCQEHCNGKFLVAVAGGMYFNIRSTSNLTTIHGVICGKYHGAAHNANNDVVMTACLLDDMLKQHTPSTEGPTKHDEFGTWRKVKPCLDNPNDRVYGSTYYHKSSRVNTSNAGAISNQMPVNKEHTDSYVIIPPAMRIKACHAVSRIHCCTACLNHGKNWLKTNLANIQQGWQLEDSNFELQLTQYEKQLKLSAEVIETPMGLRVRLGGHTGVTVNWQGSLDQTICKYNHEVNQPLPIKEVLNGLAINCTVNCSHHAVPITTEDRLNDWDTPLVVKPIQHKGTQYVCKPAGKGADNTKAFVLGMDDWVRVNYDELPRYQLTRLDNNVEVELENTLYSTGRLATQDYWTFPSEESTDCAHIELGDYNDSSLKIGGMHMFPKAFENASLNKVEQEASTPLWHANIVAKQGTKLHNSLVDVEVTRFISTIKDKLTTNTISTRTTIRIDHQNIPIMIWATAGKIDTAYLQNGGPDVVLPATQKCSQSYIQYKPVIRPYKTEVLMNSNIAHFEVLRNRLNQAANITKYVQLCNYLNDNVKVPPKTRVLHLGAATGPEHDQIPVGGVVLNHFFTNCDVYHHDIRPINNCNGRFKVGLPEGKVDLIISDIWNYNEDTDGEWISNHEMLINYVNQHLHLGGSIIWKTTRRSNLSYINYIASHFGQVDYMTTRGNASSSEMFVVFKYFKQEIKQPQEKDRDCWQILHHLFAYRHQHRTYVRQDSLNCDTISKHKSVYRVPKFLEGRIEKSSWASGNFIQQNS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-18Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN161569
EMBL· GenBank· DDBJ
QFU19787.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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