A0A5P1FAS3 · A0A5P1FAS3_ASPOF

Function

function

Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functiondiphosphoinositol-pentakisphosphate kinase activity
Molecular Functioninositol heptakisphosphate kinase activity
Molecular Functioninositol hexakisphosphate 1-kinase activity
Molecular Functioninositol hexakisphosphate 3-kinase activity
Molecular Functioninositol hexakisphosphate 5-kinase activity
Molecular Functioninositol-1,3,4,5,6-pentakisphosphate kinase activity
Biological Processinositol metabolic process
Biological Processinositol phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • EC number

Gene names

    • ORF names
      A4U43_C03F15140

Organism names

  • Taxonomic identifier
  • Strain
    • cv. DH0086
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Asparagales > Asparagaceae > Asparagoideae > Asparagus

Accessions

  • Primary accession
    A0A5P1FAS3

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region302-415Disordered
Compositional bias313-345Polar residues
Compositional bias346-369Basic and acidic residues
Domain442-523VIP1 N-terminal
Region1229-1271Disordered

Sequence similarities

Belongs to the histidine acid phosphatase family. VIP1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,461
  • Mass (Da)
    165,610
  • Last updated
    2020-02-26 v1
  • Checksum
    582F740C8AB856BC
MASVSSSDVSEGPVLNLITKKLRALKKKHNRIIQLEESQAQGKTLNKEQEDLLKSKLSVSVLILITKKLRALKKKHNRIIQLEESQAQGKTLNKEQEDLLKFTSSFLTKTHERGCCLTYDYVTDDATDLLGEGDLDMISALSALLTSRPVYSGVSHKNALEVCIERAKLWLENSDQPILEGTSATYAGLREKLKKIMALDYFTMTPEMKAPVDVAVLAFELLFTIQPRRCADINSCDGIDGQGIGGVIGFIMIVLRSLLICVYHEKLCDIFLIGYGLVEIKYEKLALLETTELQYNLQSLPSYKEDEQGESQAVESSGDQSSPPNESENVDETQIPSGDSLTVQQEQERVETDMERSQRDPDHKEQQQYIPRRGYQNQRGGRGGGGGARRGYPNGRVGRGGRGGGSGRYQNGQNQQYYDSGSYRDGAYNDFQMKLDAYADCRHKVFSAPMGQILDRLQAFGEFEVIFFGDKVILEEPVENWPICDCLIAFHSTGYPLKKAEMYAALRKPFLVNELEPQYLLHDRRKVYERLEMFGVPVPNYALVNREFPYQELDYFVEQEDFVEVRGKRFWKPFVEKPIDGDNHSIMIYYPSSAGGGMKELFRKVGNRSSEFHPDVRRVRREGSYIYEEFMSTGGTDVKVYTVGPEYAHAEARKSPVVDGVVMRNPDGKEVRYPVLLTPGEKQMARDVCLAFRQGVCGFDLLRCEGRSYVCDVNGWSFVKNSYKYYDDAACVLRKMFLDAKAPHLSSTIPPTLPWKMNEPTPPCEPLTRQGSGIIGTFGQSEELRCVIAVIRHGDRTPKQKVKLKVTEEKLLNLMLKYNGHRPRAETKLKSAVQLQDLLDATRMLVPRTRSGRESDSDAEELEHAEKLRQVKAVLEEGGHFSGIYRKVQLKPLKWVKVPKSNGDGEEERPIEALMVLKYGGVLTHAGRKQAEELGRYFRNNMYPGEGTGLLRLHSTYRHDLKIYSSDEGRVQMSAAAFAKGLLDLEGQLTPILVSLVSKDSSMLDGLENASTEMEEAKAKLHGWAEYPWMVDGAGLPSNASELLPKMIKLTKKITGQVKLLAQDEDEKLAMKSSYEVLPPYDQAKALGKTNIDVARIAAGLPCGSEGFLLMFARWRKLERDLYNERKDRFDITQIPDVYDSCKYDLLHNAHLNLDGLTELFKVAQLLADGVIPNEYGINPKHKLKIGSKIARRLLGKILIDLRNTREEAMSVAELKSNEDPTSLFLNLKKEEGDTPRHQNKSEDRRSSSTSERSLEQDDDEDKETKYRLDPKYANVKTPGRHVRTRLYFTSESHIHSLMNVLRYCNLDESLQGEESLVCNSGLERLHKTRELDYMSYIVLRMFENVEVPLEDPKRFRIEMTFSRGADLSPLENDDGEAAMLHQEHTLPINGPERLQEIGSYLTLDKMEKMIRPFAMPAEDFPPATPQAFSGYFSKSVLERLVNLWPFHKNTAVVQNNDYKI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias313-345Polar residues
Compositional bias346-369Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM007383
EMBL· GenBank· DDBJ
ONK75272.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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