A0A5N4EJ85 · A0A5N4EJ85_CAMDR
- ProteinSolute carrier family 15 member 2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids760 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-alanyl-L-alanine(out) + 2 H+(out) = L-alanyl-L-alanine(in) + 2 H+(in)This reaction proceeds in the forward direction.L-alanyl-L-alanine (out)CHEBI:195181
+ 2 H+ (out)CHEBI:15378= L-alanyl-L-alanine (in)CHEBI:195181+ 2 H+ (in)CHEBI:15378 - N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) + 3 H+(out) = N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) + 3 H+(in)This reaction proceeds in the forward direction.
- a dipeptide(out) + 2 H+(out) = a dipeptide(in) + 2 H+(in)This reaction proceeds in the forward direction.
- an L-amino acid tripeptide(out) + 2 H+(out) = an L-amino acid tripeptide(in) + 2 H+(in)This reaction proceeds in the forward direction.
- carnosine(out) + 2 H+(out) = carnosine(in) + 2 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-glutamate(out) + 3 H+(out) = glycyl-L-glutamate(in) + 3 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-leucine(out) + 2 H+(out) = glycyl-L-leucine + 2 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-lysine(out) + 2 H+(out) = glycyl-L-lysine(in) + 2 H+(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | phagocytic vesicle membrane | |
Molecular Function | dipeptide transmembrane transporter activity | |
Molecular Function | symporter activity | |
Biological Process | dipeptide import across plasma membrane | |
Biological Process | innate immune response | |
Biological Process | peptide transport | |
Biological Process | protein transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSolute carrier family 15 member 2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Tylopoda > Camelidae > Camelus
Accessions
- Primary accessionA0A5N4EJ85
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cytoplasmic vesicle, phagosome membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 69-89 | Helical | |||
Transmembrane | 95-115 | Helical | |||
Transmembrane | 127-148 | Helical | |||
Transmembrane | 154-175 | Helical | |||
Transmembrane | 196-216 | Helical | |||
Transmembrane | 228-248 | Helical | |||
Transmembrane | 309-327 | Helical | |||
Transmembrane | 357-378 | Helical | |||
Transmembrane | 390-408 | Helical | |||
Transmembrane | 678-700 | Helical | |||
Transmembrane | 706-728 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Interacts (via extracellular domain region) with trypsin.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-45 | Disordered | |||
Compositional bias | 13-33 | Polar residues | |||
Sequence similarities
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length760
- Mass (Da)85,220
- Last updated2020-02-26 v1
- ChecksumF28D5598CBDEE079
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A5N4EJQ0 | A0A5N4EJQ0_CAMDR | Cadr_000000739 | 740 | ||
A0A5N4EJW7 | A0A5N4EJW7_CAMDR | Cadr_000000739 | 694 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 13-33 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JWIN03000001 EMBL· GenBank· DDBJ | KAB1283563.1 EMBL· GenBank· DDBJ | Genomic DNA |