A0A5N3P2Z8 · A0A5N3P2Z8_9HYPH

  • Protein
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • Gene
    trmL
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site102S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site122S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site130S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      FEZ63_24640

Organism names

  • Taxonomic identifier
  • Strain
    • CDVBN77
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylobacteriaceae > Microvirga

Accessions

  • Primary accession
    A0A5N3P2Z8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-141tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    158
  • Mass (Da)
    17,389
  • Last updated
    2020-02-26 v1
  • Checksum
    E7F47552D2691704
MPRLAIYQPDIPQNTGTMLRLAACLGVPVEIIEPAGFDVSDRNLRRSGMDYLDQVKITRHISWRAFAEWRRGTEGRLVLATTKGAISYADFTFQPADIILVGRESAGVPEEVHEAADARLLVPMQQGLRSLNVAVTAAMILGEALRQTGTFPRPLSET

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VCMV01000081
EMBL· GenBank· DDBJ
KAB0264099.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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