A0A5M9Z1J7 · A0A5M9Z1J7_9LACO

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

Type
IDPosition(s)Description
Binding site8Mg2+ (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site89substrate
Active site146Proton donor/acceptor
Site178Transition state stabilizer
Binding site206-210ATP (UniProtKB | ChEBI)
Site239Transition state stabilizer
Binding site281-283ATP (UniProtKB | ChEBI)
Binding site333-337ATP (UniProtKB | ChEBI)
Binding site384Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetate kinase activity
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Biological Processacetate metabolic process
Biological Processacetyl-CoA biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • ORF names
      F1C09_07705

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCK2488
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus

Accessions

  • Primary accession
    A0A5M9Z1J7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    399
  • Mass (Da)
    44,049
  • Last updated
    2020-02-26 v1
  • Checksum
    2B467FEDBF680959
MKKILAINSGSSSFKFKLFTFPDEKVISEGMADRVGLNGSTFTIKVKGEKHQEKVDIPDSETAVTILLENLKKYDLIDDPKEIIGIGHRIVAGGEEFKDSTLIDEKSLQKIYDLKQYAPLHNTAEADVIKAFMKVLPGVPEVAVFDTSFHQTLDPVHYLYSLPYKYYEKYGARKYGAHGTSVRYVSQKAAEIMKRDLKDLKLIVCHLGSGASVTAVKDGKSFDTSMGFSPMAGITMSSRSGDVDPSLLAFVMKKENLDADQMLKVLNNESGLLGISGISPDMRDLRGDMTKLEGEKKKRADLARNIFINRIIRYVGAYTLEMRGLDGIAFTAGVGEHDFGVREHVMDSLELLGLKPDSAANKENATIITKPNSTIVGMVIPTNEELMIERDVVRVAGLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VUAV01000048
EMBL· GenBank· DDBJ
KAA8812113.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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