A0A5M8ZIR3 · A0A5M8ZIR3_9PROT

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14ADP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site14sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site18ADP (UniProtKB | ChEBI)
Binding site83glycerol (UniProtKB | ChEBI)
Binding site83sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site135glycerol (UniProtKB | ChEBI)
Binding site135sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site244glycerol (UniProtKB | ChEBI)
Binding site244sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245glycerol (UniProtKB | ChEBI)
Binding site266ADP (UniProtKB | ChEBI)
Binding site266ATP (UniProtKB | ChEBI)
Binding site309ADP (UniProtKB | ChEBI)
Binding site309ATP (UniProtKB | ChEBI)
Binding site410ADP (UniProtKB | ChEBI)
Binding site410ATP (UniProtKB | ChEBI)
Binding site414ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      FKW31_01660

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DmW_136
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Acetobacter

Accessions

  • Primary accession
    A0A5M8ZIR3

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-251Carbohydrate kinase FGGY N-terminal
Domain261-449Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    499
  • Mass (Da)
    54,666
  • Last updated
    2020-02-26 v1
  • Checksum
    54414561E7E8BA64
MSKQDCVLAIDQGTTSTRSIVFDRDAQELAAAREEFAQHYPKAGWVEHCPEDIWKDVVNTARTALEKSGAADRVAGIGITNQRETIVVWERATGKPIHRAIVWQDRRTANVCQKLRDEGAETLVRERTGLLIDPYFSATKLAWLLDNVPQARERAEKGELAFGTIDSFILWRLTGGKVHATDVTNASRTMLFDIHRQQWDEDLLRLFRVPAALLPEVKDSSCIYGETDPELFGRSIPIAGIAGDQQAAVVGQACFTPGMAKATYGTGCFLLLNTGDKPVTSRNRMLTTIAYRINGKTTYALEGSIFVAGAAIKWLRDGLHLITHASQTDDMATRVPDSHGVYMVPGFVGLGAPHWDPDARGLICGLTLDSSAAHIARAALESVAYQTLDLVTAMMQDGGGTTDSIRVDGGMSANDWYCQFLADMLQAKVERPRNVETTALGAGFLAGIATGVWDSEQTVASEWARGSLFEPKMENEQRRTMIAGWHQAVKRTLSTYTGS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHON01000005
EMBL· GenBank· DDBJ
KAA8388415.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help