A0A5K1K4T7 · A0A5K1K4T7_9APHY

  • Protein
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • Gene
    K9FDB7
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster.
[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionelectron transfer activity
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processphosphorylation
Biological Processrespiratory electron transport chain
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • EC number

Gene names

    • Name
      K9FDB7

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Polyporaceae > Ganoderma

Accessions

  • Primary accession
    A0A5K1K4T7

Subcellular Location

Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-1312Fe-2S ferredoxin-type
Domain172-2024Fe-4S ferredoxin-type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    269
  • Mass (Da)
    30,719
  • Last updated
    2019-12-11 v1
  • MD5 Checksum
    74AAD4EC07A198E9E2FBB52694B0FF8E
MQSLVAPRSSVLKHTFRGFASSAARAQATPLQKPALNKEFKIYRWNPDEPSKKPTLQSYTIDLNQCGPMILDALIKIKNEIDPTLTFRRSCREGICGSCAMNINGQNTLACLCRIDRNASKDTKIYPLPHMYIVKDLVPDLTQFYKQYKSIEPYLLNDNPPADREFLQSPEDRKKLDGMYECILCACCSTSCPSYWWNQDEYLGPATLMAAYRWMADSRDTYKAHRMEKMQNELSLYRCHTIFNCARTCPKGLNPAAAIAKMKLELASE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR728872
EMBL· GenBank· DDBJ
VWP00848.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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