A0A5I9C545 · A0A5I9C545_SALET

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site118Important for catalytic activity
Site140Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Molecular Function3-hydroxybutyryl-CoA epimerase activity
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • ORF names
      APM01_04245
      , DN927_23535
      , DOG83_12220
      , DU046_19640
      , DYS13_05205
      , DYT81_19705
      , E5908_14365
      , EWI81_16050

Organism names

  • Taxonomic identifier
  • Strains
    • FSIS11811772
    • FSIS11812504
    • FSIS31800512
    • FSIS31800555
    • FSIS31800800
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella

Accessions

  • Primary accession
    A0A5I9C545

Subcellular Location

Keywords

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-190Enoyl-CoA hydratase
Region306-7153-hydroxyacyl-CoA dehydrogenase
Domain311-4893-hydroxyacyl-CoA dehydrogenase NAD binding
Domain492-5863-hydroxyacyl-CoA dehydrogenase C-terminal

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    715
  • Mass (Da)
    77,424
  • Last updated
    2019-12-11 v1
  • Checksum
    2AF868D1C387355F
MTTTSAFMLNVRLDNVAVVAIDVPREKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAIFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNRETDQGN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHXHM010000029
EMBL· GenBank· DDBJ
ECB3378412.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHYZU010000012
EMBL· GenBank· DDBJ
ECB8845817.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKIXE010000002
EMBL· GenBank· DDBJ
ECS2227567.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKLKV010000048
EMBL· GenBank· DDBJ
ECT0134942.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKLWJ010000074
EMBL· GenBank· DDBJ
ECT1544628.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKMFT010000088
EMBL· GenBank· DDBJ
ECT2693215.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKSPP010000007
EMBL· GenBank· DDBJ
ECV1596252.1
EMBL· GenBank· DDBJ
Genomic DNA
AAKSBI010000015
EMBL· GenBank· DDBJ
ECV3389413.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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