A0A5F9ZHL4 · A0A5F9ZHL4_HUMAN

  • Protein
    non-specific protein-tyrosine kinase
  • Gene
    TNK2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

Features

Showing features for binding site.

128920406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site222ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionprotein tyrosine kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific protein-tyrosine kinase
  • EC number

Gene names

    • Name
      TNK2

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A5F9ZHL4

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Genetic variation databases

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region154-178Disordered
Domain190-289Protein kinase

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    289
  • Mass (Da)
    32,375
  • Last updated
    2019-12-11 v1
  • Checksum
    9C83DF9A6A506DE2
MRSGALGPRGRGRASALGLPVPAMASRQCWARHPRVGLCWAAFEQESGPSCHRSEVKERLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFL

Computationally mapped potential isoform sequences

There are 19 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q07912ACK1_HUMANTNK21038
C9J1X3C9J1X3_HUMANTNK21040
A0A5F9ZH01A0A5F9ZH01_HUMANTNK2301
A0A5F9ZH66A0A5F9ZH66_HUMANTNK295
A0A5F9ZHI7A0A5F9ZHI7_HUMANTNK2143
A0A5F9ZHJ2A0A5F9ZHJ2_HUMANTNK21072
A0A5F9ZHK8A0A5F9ZHK8_HUMANTNK292
A0A5F9ZHP4A0A5F9ZHP4_HUMANTNK21008
A0A5F9ZHP9A0A5F9ZHP9_HUMANTNK297
A0A5F9ZHQ1A0A5F9ZHQ1_HUMANTNK2154
A0A5F9ZI29A0A5F9ZI29_HUMANTNK21040
A0A5F9ZI44A0A5F9ZI44_HUMANTNK2118
A0A5F9ZGX5A0A5F9ZGX5_HUMANTNK21055
A0A5F9ZGY5A0A5F9ZGY5_HUMANTNK2153
A0A5F9ZHX6A0A5F9ZHX6_HUMANTNK2144
A0A5F9ZHB0A0A5F9ZHB0_HUMANTNK2280
A0A5F9ZHC7A0A5F9ZHC7_HUMANTNK298
A0A5F9ZHD0A0A5F9ZHD0_HUMANTNK2550
A0A499FJ16A0A499FJ16_HUMANTNK21086

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue289

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC124944
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help