A0A5F9ZHL4 · A0A5F9ZHL4_HUMAN
- Proteinnon-specific protein-tyrosine kinase
- GeneTNK2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids289 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 222 | ATP (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | protein tyrosine kinase activity | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific protein-tyrosine kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A5F9ZHL4
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Expression
Gene expression databases
Structure
Sequence
- Sequence statusFragment
- Length289
- Mass (Da)32,375
- Last updated2019-12-11 v1
- Checksum9C83DF9A6A506DE2
Computationally mapped potential isoform sequences
There are 19 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q07912 | ACK1_HUMAN | TNK2 | 1038 | ||
C9J1X3 | C9J1X3_HUMAN | TNK2 | 1040 | ||
A0A5F9ZH01 | A0A5F9ZH01_HUMAN | TNK2 | 301 | ||
A0A5F9ZH66 | A0A5F9ZH66_HUMAN | TNK2 | 95 | ||
A0A5F9ZHI7 | A0A5F9ZHI7_HUMAN | TNK2 | 143 | ||
A0A5F9ZHJ2 | A0A5F9ZHJ2_HUMAN | TNK2 | 1072 | ||
A0A5F9ZHK8 | A0A5F9ZHK8_HUMAN | TNK2 | 92 | ||
A0A5F9ZHP4 | A0A5F9ZHP4_HUMAN | TNK2 | 1008 | ||
A0A5F9ZHP9 | A0A5F9ZHP9_HUMAN | TNK2 | 97 | ||
A0A5F9ZHQ1 | A0A5F9ZHQ1_HUMAN | TNK2 | 154 | ||
A0A5F9ZI29 | A0A5F9ZI29_HUMAN | TNK2 | 1040 | ||
A0A5F9ZI44 | A0A5F9ZI44_HUMAN | TNK2 | 118 | ||
A0A5F9ZGX5 | A0A5F9ZGX5_HUMAN | TNK2 | 1055 | ||
A0A5F9ZGY5 | A0A5F9ZGY5_HUMAN | TNK2 | 153 | ||
A0A5F9ZHX6 | A0A5F9ZHX6_HUMAN | TNK2 | 144 | ||
A0A5F9ZHB0 | A0A5F9ZHB0_HUMAN | TNK2 | 280 | ||
A0A5F9ZHC7 | A0A5F9ZHC7_HUMAN | TNK2 | 98 | ||
A0A5F9ZHD0 | A0A5F9ZHD0_HUMAN | TNK2 | 550 | ||
A0A499FJ16 | A0A499FJ16_HUMAN | TNK2 | 1086 |
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 289 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC124944 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |