A0A5F9ZHE0 · A0A5F9ZHE0_HUMAN

  • Protein
    Phosphotransferase
  • Gene
    GCK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionD-glucose binding
Molecular Functionglucokinase activity
Biological Processglycolytic process
Biological Processhexose metabolic process
Biological Processintracellular glucose homeostasis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphotransferase
  • EC number

Gene names

    • Name
      GCK

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A5F9ZHE0

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Variants

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The viewer provides 611 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Expression

Gene expression databases

Family & Domains

Features

Showing features for coiled coil, domain.

TypeIDPosition(s)Description
Coiled coil13-40
Domain16-215Hexokinase N-terminal
Domain222-287Hexokinase C-terminal
Domain309-476Hexokinase C-terminal

Sequence similarities

Belongs to the hexokinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    486
  • Mass (Da)
    54,386
  • Last updated
    2019-12-11 v1
  • Checksum
    CCC0D74620A62C27
MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGDRACRGGSETPPARFLGLTQHSPKYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P35557HXK4_HUMANGCK465
C9JQD1C9JQD1_HUMANGCK448
A0A8C8KJG0A0A8C8KJG0_HUMANGCK42
A0A5F9ZGW4A0A5F9ZGW4_HUMANGCK456
H7BXV0H7BXV0_HUMANGCK143
A0A8C8PZE6A0A8C8PZE6_HUMANGCK289

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006454
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KF458452
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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