The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation.Sun S., Kelekar S., Kliewer S.A., Mangelsdorf D.J.View abstractCategoriesInteractionSourceMGI: 98970PubMedEurope PMCGenes Dev 33:1083-1094 (2019)Mapped to18
CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.Yang R., Wang H., Kang B., Chen B., Shi Y., Yang S., Sun L., Liu Y., Xiao W.[...], Huang Y.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCDevelopment 146:0-0 (2019)Cited in3Mapped to99+
PGC-1alpha functions as a co-suppressor of XBP1s to regulate glucose metabolism.Lee J., Salazar Hernandez M.A., Auen T., Mucka P., Lee J., Ozcan U.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCMol Metab 7:119-131 (2018)Mapped to18
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.Zhao G., Fu Y., Cai Z., Yu F., Gong Z., Dai R., Hu Y., Zeng L., Xu Q., Kong W.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCCirc Res 121:1331-1345 (2017)Mapped to7
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity.Cao J., Peng J., An H., He Q., Boronina T., Guo S., White M.F., Cole P.A., He L.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCNat Commun 8:131-131 (2017)Mapped to31
Inflammation Improves Glucose Homeostasis through IKKbeta-XBP1s Interaction.Liu J., Ibi D., Taniguchi K., Lee J., Herrema H., Akosman B., Mucka P., Salazar Hernandez M.A., Uyar M.F.[...], Ozcan U.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCCell 167:1052-1066.e18 (2016)Mapped to15
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.Duplan E., Giaime E., Viotti J., Sevalle J., Corti O., Brice A., Ariga H., Qi L., Checler F., Alves da Costa C.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCJ Cell Sci 126:2124-2133 (2013)Mapped to74
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction.Zhou Y., Lee J., Reno C.M., Sun C., Park S.W., Chung J., Lee J., Fisher S.J., White M.F.[...], Ozcan U.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCNat. Med. 17:356-365 (2011)Cited in2Mapped to8
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation.Wang F.M., Chen Y.J., Ouyang H.J.View abstractCategoriesPTM / Processing, InteractionSourceMGI: 98970PubMedEurope PMCBiochem. J. 433:245-252 (2011)Cited in6Mapped to22
The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation.Park S.W., Zhou Y., Lee J., Lu A., Sun C., Chung J., Ueki K., Ozcan U.View abstractCategoriesFunction, InteractionSourceMGI: 98970PubMedEurope PMCNat. Med. 16:429-437 (2010)Cited in3Mapped to20
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response.Winnay J.N., Boucher J., Mori M.A., Ueki K., Kahn C.R.View abstractCategoriesInteractionSourceMGI: 98970PubMedEurope PMCNat. Med. 16:438-445 (2010)Cited in2Mapped to15