A0A5F8GYD2 · A0A5F8GYD2_MONDO
- Proteinhistidine--tRNA ligase
- GeneHARS2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids477 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 103-105 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 130 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 146 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 150 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 299 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 303-304 | L-histidine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | histidine-tRNA ligase activity | |
Biological Process | histidyl-tRNA aminoacylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namehistidine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Metatheria > Didelphimorphia > Didelphidae > Monodelphis
Accessions
- Primary accessionA0A5F8GYD2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 34-366 | Aminoacyl-transfer RNA synthetases class-II family profile | |||
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length477
- Mass (Da)53,906
- Last updated2019-12-11 v1
- MD5 ChecksumF57E01DFC2DACC194F20CC1B8378AD81
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F6WJC7 | F6WJC7_MONDO | HARS2 | 502 |
Keywords
- Technical term