A0A5F8GW10 · A0A5F8GW10_MONDO

Function

Catalytic activity

Activity regulation

Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular Functioncalcium ion binding
Molecular Functioncalmodulin binding
Molecular Functionelongation factor-2 kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Eukaryotic elongation factor 2 kinase
  • EC number

Gene names

    • Name
      EEF2K

Organism names

Accessions

  • Primary accession
    A0A5F8GW10

Proteomes

Expression

Gene expression databases

Interaction

Subunit

Monomer or homodimer.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain116-326Alpha-type protein kinase
Region351-403Disordered
Compositional bias369-402Polar residues
Region416-475Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    679
  • Mass (Da)
    77,429
  • Last updated
    2019-12-11 v1
  • Checksum
    7845BA889F4B164E
MADEDLIFRLEGIDNSRSPHSHHAGFSDDDSDEEDGYYICPITDDPGCNKIANSKVSNYYSNLTKNEQYGSNCSPGSSFHFKETWKHAIEKAKHMPDPWAEFHLEDIETECATRHRYNAVTGEWVEDEVLIKMASQPFGRGAMRECFRTKKLSNFLHTQHWKGASNYVAKRYIEPVNRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRADKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGSDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDLSPKEKDAVNQTIKLQSAQTLVRGTEEKCGSPRVRTFSGSRPPLLSRLSENSGDENMSDVTFDSLPSSPSFTPHSQRIDHLHWPQFSDVDNLGHKDHDQLDNHRDSENGGDSGYPSERRNELEDIDSRDKGHSNGNRKQSESDEDSLGSYGRVHLAMVRYHEGGRFCEKDQPWDQESAVFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKESEENRTKGFDYLLKAAEAGDRHSMILVARAYDTGLNLSSDRTQNWKEALRWYDTALNTTDYDEGGEYDGMQDEPRHTLLAREAEMLFTGGFQLEKDPQRSGDLYTSAAEAAMEAMKGRLANKYYEKAEEAWAMMEE

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F7C485F7C485_MONDOEEF2K724

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias369-402Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help