A0A5F8AIN4 · A0A5F8AIN4_MACMU
- ProteinPlatelet-activating factor acetylhydrolase
- GenePLA2G7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids416 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
Catalytic activity
- 1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-O-dodecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-dodecyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 10-hydroperoxy-(8E)-octadecenoate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 5-oxopentanoate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-[9-hydroperoxy-(10E-octadecenoyl)]-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-hydroperoxy-10E-octadecenoate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + butanoate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + glutarate + H+This reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+ + pentanoateThis reaction proceeds in the forward direction.
- 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+ + propanoateThis reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 250 | Nucleophile | ||||
Sequence: S | ||||||
Active site | 273 | Nucleophile | ||||
Sequence: D | ||||||
Active site | 328 | Charge relay system | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | 1-alkyl-2-acetylglycerophosphocholine esterase activity | |
Biological Process | lipid catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePlatelet-activating factor acetylhydrolase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionA0A5F8AIN4
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-21 | |||||
Sequence: MVPPKLCVLFCLCGCLAVVHP | ||||||
Chain | PRO_5023927171 | 22-416 | Platelet-activating factor acetylhydrolase | |||
Sequence: FDWQYLNPVAHMKSSAWVNKIQVLMAAASFGEAKIPKGNGPYSVGCTDLMFDHTKKGTFLRLYYPSQDDDRLDTLWIPNKEYFWGLSKYLGKHWLMGNILSLLFGSVTTPANWNSPLRPGEKYPLVVFSHGLGAFRDRSASATYYFKNQSAAEIGKKSWLYLRTLKEEEEIHIRNKQVRQRAKECSQALNLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMLPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGRMLKLKGDIDSDVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTTNQHIMLQSSSGTEN |
Keywords
- PTM
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length416
- Mass (Da)47,201
- Last updated2019-12-11 v1
- Checksum5FFB41B14B2FCCF4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
F6SQA6 | F6SQA6_MACMU | PLA2G7 | 439 |
Keywords
- Technical term