A0A5F8AIN4 · A0A5F8AIN4_MACMU

Function

Catalytic activity

  • 1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-O-dodecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-dodecyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 10-hydroperoxy-(8E)-octadecenoate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 5-oxopentanoate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-[9-hydroperoxy-(10E-octadecenoyl)]-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-hydroperoxy-10E-octadecenoate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + butanoate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + glutarate + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+ + pentanoate
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+ + propanoate
    This reaction proceeds in the forward direction.
  • a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H+
    This reaction proceeds in the forward direction.
    EC:3.1.1.47 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site250Nucleophile
Active site273Nucleophile
Active site328Charge relay system

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Function1-alkyl-2-acetylglycerophosphocholine esterase activity
Biological Processlipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Platelet-activating factor acetylhydrolase
  • EC number

Gene names

    • Name
      PLA2G7

Organism names

  • Taxonomic identifier
  • Strain
    • 17573
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca

Accessions

  • Primary accession
    A0A5F8AIN4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_502392717122-416Platelet-activating factor acetylhydrolase

Keywords

Expression

Gene expression databases

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    416
  • Mass (Da)
    47,201
  • Last updated
    2019-12-11 v1
  • Checksum
    5FFB41B14B2FCCF4
MVPPKLCVLFCLCGCLAVVHPFDWQYLNPVAHMKSSAWVNKIQVLMAAASFGEAKIPKGNGPYSVGCTDLMFDHTKKGTFLRLYYPSQDDDRLDTLWIPNKEYFWGLSKYLGKHWLMGNILSLLFGSVTTPANWNSPLRPGEKYPLVVFSHGLGAFRDRSASATYYFKNQSAAEIGKKSWLYLRTLKEEEEIHIRNKQVRQRAKECSQALNLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMLPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGRMLKLKGDIDSDVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTTNQHIMLQSSSGTEN

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F6SQA6F6SQA6_MACMUPLA2G7439

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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