A0A5F7ZZM6 · A0A5F7ZZM6_MACMU
- ProteinNuclear mitotic apparatus protein 1
- GeneNUMA1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2154 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Cercopithecoidea > Cercopithecidae (Old World monkeys) > Cercopithecinae > Macaca (macaques)
Accessions
- Primary accessionA0A5F7ZZM6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
- centrosome
- cortical microtubule
- cytoplasmic microtubule bundle
- cytosol
- lateral cell cortex
- microtubule minus-end
- microtubule plus-end
- mitotic spindle astral microtubule
- mitotic spindle midzone
- mitotic spindle pole
- nuclear matrix
- nucleoplasm
- plasma membrane
- protein-containing complex
- spindle microtubule
- spindle pole
- spindle pole centrosome
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Family & Domains
Features
Showing features for domain, coiled coil, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 80-189 | Nuclear mitotic apparatus protein 1 N-terminal hook | ||||
Sequence: HGTEEGQQILQQPVPERLDFVCSFLQKNQKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLRK | ||||||
Coiled coil | 252-286 | |||||
Sequence: MRRLKKQLADERSNRDELELELAENRKLLTEKDAQ | ||||||
Compositional bias | 582-600 | Polar residues | ||||
Sequence: SQGLRHQVEQLSSSLKQKE | ||||||
Region | 582-629 | Disordered | ||||
Sequence: SQGLRHQVEQLSSSLKQKEQQLKEVAEKQEVTRRDHAQQLATAAEERE | ||||||
Compositional bias | 601-629 | Basic and acidic residues | ||||
Sequence: QQLKEVAEKQEVTRRDHAQQLATAAEERE | ||||||
Compositional bias | 962-990 | Basic and acidic residues | ||||
Sequence: AGEQQETASRELVKEPARAGDREPEWLEE | ||||||
Region | 962-993 | Disordered | ||||
Sequence: AGEQQETASRELVKEPARAGDREPEWLEEQQG | ||||||
Region | 1026-1050 | Disordered | ||||
Sequence: ESQGQQQEERGQQEREVARLTQERG | ||||||
Compositional bias | 1033-1050 | Basic and acidic residues | ||||
Sequence: EERGQQEREVARLTQERG | ||||||
Compositional bias | 1126-1140 | Basic and acidic residues | ||||
Sequence: LKEQLAKKEKEHASG | ||||||
Region | 1126-1261 | Disordered | ||||
Sequence: LKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQQQQEQADSLERSLEAERASRAERDSALETLQGQLEEKARELGHSQSALASVQRELAALRTKVQDHSKAEDEWKAQVARGRQEAERKNS | ||||||
Compositional bias | 1167-1181 | Polar residues | ||||
Sequence: KLEQQCQQQQEQADS | ||||||
Compositional bias | 1182-1215 | Basic and acidic residues | ||||
Sequence: LERSLEAERASRAERDSALETLQGQLEEKARELG | ||||||
Compositional bias | 1231-1261 | Basic and acidic residues | ||||
Sequence: LRTKVQDHSKAEDEWKAQVARGRQEAERKNS | ||||||
Region | 1311-1356 | Disordered | ||||
Sequence: ETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE | ||||||
Compositional bias | 1322-1345 | Basic and acidic residues | ||||
Sequence: RSSALREEVQSLREEAEKQRVASE | ||||||
Coiled coil | 1403-1729 | |||||
Sequence: CQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEEKQKLTAQVEQLEVFQREQTKQVEELRKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQARLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLQSLEHLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQ | ||||||
Compositional bias | 1770-1792 | Polar residues | ||||
Sequence: PLSITSKLPRTQPDGTSVPGEPA | ||||||
Region | 1770-1797 | Disordered | ||||
Sequence: PLSITSKLPRTQPDGTSVPGEPASPISQ | ||||||
Region | 1862-1937 | Disordered | ||||
Sequence: EEPDSANSSFYSTRSAPASQASLRATSSTQSLARLSSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNS | ||||||
Compositional bias | 1866-1931 | Polar residues | ||||
Sequence: SANSSFYSTRSAPASQASLRATSSTQSLARLSSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGA | ||||||
Compositional bias | 2004-2023 | Polar residues | ||||
Sequence: ASMQPIQIAEGTGITTRQQR | ||||||
Region | 2004-2132 | Disordered | ||||
Sequence: ASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSATEAQKKAAPASTKQADQRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTAS | ||||||
Compositional bias | 2050-2064 | Basic and acidic residues | ||||
Sequence: MTPRDRHEGRKQSAT | ||||||
Compositional bias | 2067-2094 | Polar residues | ||||
Sequence: QKKAAPASTKQADQRQSMAFSILNTPKK | ||||||
Compositional bias | 2109-2132 | Polar residues | ||||
Sequence: LSKASPNTRSGTRRSPRIATTTAS |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,154
- Mass (Da)242,940
- Last updated2019-12-11 v1
- ChecksumEA53C7FABC39C342
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A5F7ZIZ3 | A0A5F7ZIZ3_MACMU | NUMA1 | 2104 | ||
F7EE62 | F7EE62_MACMU | NUMA1 | 2118 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 582-600 | Polar residues | ||||
Sequence: SQGLRHQVEQLSSSLKQKE | ||||||
Compositional bias | 601-629 | Basic and acidic residues | ||||
Sequence: QQLKEVAEKQEVTRRDHAQQLATAAEERE | ||||||
Compositional bias | 962-990 | Basic and acidic residues | ||||
Sequence: AGEQQETASRELVKEPARAGDREPEWLEE | ||||||
Compositional bias | 1033-1050 | Basic and acidic residues | ||||
Sequence: EERGQQEREVARLTQERG | ||||||
Compositional bias | 1126-1140 | Basic and acidic residues | ||||
Sequence: LKEQLAKKEKEHASG | ||||||
Compositional bias | 1167-1181 | Polar residues | ||||
Sequence: KLEQQCQQQQEQADS | ||||||
Compositional bias | 1182-1215 | Basic and acidic residues | ||||
Sequence: LERSLEAERASRAERDSALETLQGQLEEKARELG | ||||||
Compositional bias | 1231-1261 | Basic and acidic residues | ||||
Sequence: LRTKVQDHSKAEDEWKAQVARGRQEAERKNS | ||||||
Compositional bias | 1322-1345 | Basic and acidic residues | ||||
Sequence: RSSALREEVQSLREEAEKQRVASE | ||||||
Compositional bias | 1770-1792 | Polar residues | ||||
Sequence: PLSITSKLPRTQPDGTSVPGEPA | ||||||
Compositional bias | 1866-1931 | Polar residues | ||||
Sequence: SANSSFYSTRSAPASQASLRATSSTQSLARLSSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGA | ||||||
Compositional bias | 2004-2023 | Polar residues | ||||
Sequence: ASMQPIQIAEGTGITTRQQR | ||||||
Compositional bias | 2050-2064 | Basic and acidic residues | ||||
Sequence: MTPRDRHEGRKQSAT | ||||||
Compositional bias | 2067-2094 | Polar residues | ||||
Sequence: QKKAAPASTKQADQRQSMAFSILNTPKK | ||||||
Compositional bias | 2109-2132 | Polar residues | ||||
Sequence: LSKASPNTRSGTRRSPRIATTTAS |
Keywords
- Technical term