A0A5F7ZZG9 · A0A5F7ZZG9_MACMU

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site1588ATP (UniProtKB | ChEBI)
Binding site1612ATP (UniProtKB | ChEBI)
Binding site1684ATP (UniProtKB | ChEBI)
Binding site1717Zn2+ (UniProtKB | ChEBI)
Active site1731Proton acceptor
Binding site1733ATP (UniProtKB | ChEBI)
Binding site1741ATP (UniProtKB | ChEBI)
Binding site1758-1764ATP (UniProtKB | ChEBI)
Binding site1774Zn2+ (UniProtKB | ChEBI)
Binding site1776Zn2+ (UniProtKB | ChEBI)
Binding site1780Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular FunctionATP binding
Molecular Functioncalcium channel activity
Molecular Functionhistone H2AS1 kinase activity
Molecular Functionmetal ion binding
Biological Processprotein phosphorylation
Biological Processprotein tetramerization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      TRPM7

Organism names

  • Taxonomic identifier
  • Strain
    • 17573
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca

Accessions

  • Primary accession
    A0A5F7ZZG9

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane741-759Helical
Transmembrane839-861Helical
Transmembrane906-928Helical
Transmembrane940-959Helical
Transmembrane980-999Helical
Transmembrane1061-1084Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Expression

Gene expression databases

Structure

3D structure databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias527-545Polar residues
Region527-557Disordered
Domain1558-1788Alpha-type protein kinase
Region1800-1829Disordered
Compositional bias1807-1829Polar residues

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,829
  • Mass (Da)
    208,506
  • Last updated
    2019-12-11 v1
  • Checksum
    B89ACF44EB2E1252
YIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNEAVHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVVEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQIKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHSIVNTLSSSVPQGDLESNNPFLCNILMKDDKDPQCNIFGQDLPAIPQRKEFNFPEAGSSSGALFASAGSPPELRQRLHGVELLKIFNKNQKLGSSSNSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKAAEGDNIEFGAFVGHRDSMDLQRFKETSNKIKEILFNNNTSEKTLKRVSSLAGFTDCHRTSIPLHSKQEKISRRPSTEDTHEVDSKAALIPVCLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A5F8AAE9A0A5F8AAE9_MACMUTRPM71866
F6UIC3F6UIC3_MACMUTRPM71865
A0A5F7ZQX0A0A5F7ZQX0_MACMUTRPM71993
A0A5F8ATQ0A0A5F8ATQ0_MACMUTRPM72379
F6ZE09F6ZE09_MACMUTRPM72361
A0A1D5QLT0A0A1D5QLT0_MACMUTRPM7538
A0A5F8AQF5A0A5F8AQF5_MACMUTRPM71823

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias527-545Polar residues
Compositional bias1807-1829Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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