A0A5F7Z9F0 · A0A5F7Z9F0_MACMU

Function

function

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcaveola
Cellular Componentdystrophin-associated glycoprotein complex
Cellular Componentendoplasmic reticulum
Cellular ComponentGolgi membrane
Cellular ComponentT-tubule
Molecular Functionalpha-tubulin binding
Molecular Functioncalcium channel regulator activity
Molecular Functionconnexin binding
Molecular Functionmolecular adaptor activity
Molecular Functionprotein-containing complex binding
Molecular Functionsodium channel regulator activity
Molecular Functiontransmembrane transporter binding
Biological Processactin filament organization
Biological Processcalcium ion transport
Biological Processcardiac muscle cell development
Biological Processcardiac muscle hypertrophy
Biological Processcaveola assembly
Biological Processcell differentiation
Biological Processcholesterol homeostasis
Biological Processcytoplasmic microtubule organization
Biological Processdetection of muscle stretch
Biological Processestablishment of localization in cell
Biological Processglucose homeostasis
Biological Processheart trabecula formation
Biological ProcessMAPK cascade
Biological Processmyoblast fusion
Biological Processnegative regulation of calcium ion transport
Biological Processnegative regulation of cardiac muscle hypertrophy
Biological Processnegative regulation of cell size
Biological Processnegative regulation of MAPK cascade
Biological Processnegative regulation of membrane depolarization during cardiac muscle cell action potential
Biological Processnegative regulation of sarcomere organization
Biological Processnucleus localization
Biological Processplasma membrane repair
Biological Processpositive regulation of myotube differentiation
Biological Processprotein localization to plasma membrane
Biological Processregulation of branching involved in mammary gland duct morphogenesis
Biological Processregulation of calcium ion import
Biological Processregulation of cardiac muscle cell action potential involved in regulation of contraction
Biological Processregulation of cytosolic calcium ion concentration
Biological Processregulation of heart rate
Biological Processregulation of membrane potential
Biological Processregulation of p38MAPK cascade
Biological Processregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processregulation of signal transduction by receptor internalization
Biological Processregulation of skeletal muscle contraction
Biological Processregulation of transforming growth factor beta receptor signaling pathway
Biological Processregulation of ventricular cardiac muscle cell membrane depolarization
Biological Processregulation of ventricular cardiac muscle cell membrane repolarization
Biological Processtriglyceride metabolic process

Names & Taxonomy

Protein names

  • Recommended name
    Caveolin

Gene names

    • Name
      CAV3

Organism names

  • Taxonomic identifier
  • Strain
    • 17573
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca

Accessions

  • Primary accession
    A0A5F7Z9F0

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane, sarcolemma
Cell membrane
; Peripheral membrane protein
Golgi apparatus membrane
; Peripheral membrane protein
Membrane, caveola
; Peripheral membrane protein
Membrane
; Peripheral membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane124-147Helical

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the caveolin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    196
  • Mass (Da)
    21,942
  • Last updated
    2019-12-11 v1
  • Checksum
    C2555CAAFD37D284
MLGGAYSAGRDISLGTLNWSLCPKDFQPQPATRRGSPPVDPPSSAMMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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