A0A5F5Y7A4 · A0A5F5Y7A4_FELCA
- ProteinTriacylglycerol lipase
- GenePNLIPRP1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids467 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H+This reaction proceeds in the forward direction.
- 1,2,3-tributanoylglycerol + H2O = dibutanoylglycerol + butanoate + H+This reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+This reaction proceeds in the forward direction.
- all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + hexadecanoate + H+This reaction proceeds in the forward direction.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 170 | Nucleophile | |||
Active site | 194 | Charge relay system | |||
Binding site | 208 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 210 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 213 | Ca2+ (UniProtKB | ChEBI) | |||
Active site | 281 | Charge relay system | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity | |
Molecular Function | metal ion binding | |
Molecular Function | triacylglycerol lipase activity | |
Biological Process | lipid catabolic process |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriacylglycerol lipase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis
Accessions
- Primary accessionA0A5F5Y7A4
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-17 | ||||
Chain | PRO_5023971251 | 18-467 | Triacylglycerol lipase | ||
Disulfide bond | 21↔27 | ||||
Disulfide bond | 108↔119 | ||||
Disulfide bond | 255↔279 | ||||
Disulfide bond | 303↔314 | ||||
Disulfide bond | 317↔322 | ||||
Disulfide bond | 451↔467 | ||||
Keywords
- PTM
Expression
Gene expression databases
Interaction
Subunit
Forms a 1:1 stoichiometric complex with (pro)colipase/CLPS.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 356-467 | PLAT | |||
Sequence similarities
Belongs to the AB hydrolase superfamily. Lipase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length467
- Mass (Da)51,396
- Last updated2019-12-11 v1
- ChecksumE9F5D53B74FD6DD3
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
M3WPS6 | M3WPS6_FELCA | PNLIPRP1 | 467 | ||
A0A5F5XSU9 | A0A5F5XSU9_FELCA | PNLIPRP1 | 495 | ||
A0A5F5Y5N1 | A0A5F5Y5N1_FELCA | PNLIPRP1 | 467 | ||
A0A5F5Y684 | A0A5F5Y684_FELCA | PNLIPRP1 | 486 | ||
M3VWT0 | M3VWT0_FELCA | PNLIPRP1 | 469 | ||
A0A0A0MPX7 | A0A0A0MPX7_FELCA | PNLIPRP1 | 465 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AANG04000273 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |